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Optogenetische Stimulation des nativen Herzmuskels durch Adeno-assoziierte Virustransduktion von Channelrhodopsin-2
Vogt, Christoph Carsten Otto See Kee (2022-12-15)Die Optogenetik ist eine innovative Methode, die die transgene Expression von lichtsensitiven Proteinen verwendet zur elektrophysiologischen oder biochemischen Stimulation von Zellen durch Beleuchtung. Das Beleuchten mit ... -
OptoRiboGenetics: Post-transcriptional control of gene expression by light
Pilsl, Sebastian (2021-08-26)Gene expression is tightly regulated in mammalian cells at the post transcriptional level and its precise manipulation has proven to be valuable for protein overexpression and gene therapy. Implementation of light-responsive ... -
Oral or Parenteral Methotrexate for treatment of Non- Systemic Juvenile Idiopathic Arthritis
Bakry, Reima Ahmed (2021-04-28)Background: Methotrexate is approved and recommend as first line disease modifying antirheumatic drug (DMARD) in polyarticular juvenile idiopathic arthritis (JIA). In can be used orally or via s.c. injection. <br /> ... -
Orbifolds and Kaluza-Klein-Monopoles in Heterotic E8 x E8 String Theory Preserving Eight Supercharges
Conrad, Jan (2002)We give a detailed account on heterotic E<sub>8</sub> x E<sub>8</sub> orbifold models with N=(1,0), D=6 supersymmetry using the operator approach. It is shown that there is a weak and a strong form of the level matching ... -
Die Orchestersinfonien Felix Mendelssohn Bartholdys: Studien zum gegenwärtigen Fachdiskurs
Gömann, Silke (1999)Gegenstand der Arbeit ist der deutsche Fachdiskurs über die Orchestersinfonien Felix Mendelssohn Bartholdys seit dem Berliner Mendelssohn-Symposium 1972. Dabei richtet sich das Untersuchungsinteresse auf die Funktionsmechanismen ... -
Order-Theoretic Combination Techniques and the Electronic Schrödinger Equation
Barker, James Nicholas John (2024-05-22)Most standard constructions of the <em>combination technique</em> [M. Griebel et al., <em>Iterative Methods in Linear Algebra</em>, Elsevier, North Holland, p. 263] manipulate families of functions organised by downward-closed ... -
Ordnungsbildungen an der Schwelle zwischen Medizin und Alltagswelt: Eine situationstheoretische Studie zur pränatalen Sozialität von Kindern mit diagnostizierten Fehlbildungen
Feith, Dominik Vincenzo (2022-08-29)Die Dissertation untersucht medizinisch auffällige Schwangerschaften aus einer wissenssoziologischen Perspektive. Im Zentrum des Erkenntnisinteresses steht die Frage danach, wie sich die Diagnose einer Fehlbildung beim ... -
Ordnungsphänomene redox-aktiver Moleküle auf Elektrodenoberflächen unter reaktiven Bedingungen
Röefzaad, Melanie Sandra (2011-02-25)Im Rahmen dieser Arbeit konnte erfolgreich die IR-Reflektions-Absorptions-Spektroskopie (IRRAS) an Oberflächen mit elektrochemischen Methoden, wie der Zyklovoltammetrie (CV), und bildgebenden Methoden, wie der Rastertunn ... -
Organic-Inorganic Hybrids and Charge Transfer Salts with N-Methylpyridoneazine and its Derivatives
Isenberg, Rebecca Atima (2023-11-13)The pyridone azine N-methylpyridoneazine (MPA, 1) is electron-rich and a planar organic donor molecule. As two-stage redox system, it can undergo two one-electron oxidation steps forming a radical cation species and an ... -
Die Organisation des baulichen Raums in postklassischen Siedlungszentren des nördlichen Maya-Tieflands
Narberhaus, Mechthild (2006)In der vorliegenden Arbeit sind drei Zentren der Mittleren und Späten Postklassik aus dem nördlichen Maya-Tiefland auf die Organisation ihres baulichen Raums untersucht worden. Dies galt hinsichtlich der Frage, ob Ähnlichkeiten ... -
The Organisation of Trade in North Sumatra: Batak Traders and Trading Networks
Situmorang, Kathrin-Christine (2011-08-11)A brisk, flourishing and independent local commerce and the integration of the population into local and regional trading structures are important basic conditions for the development and welfare of a region. Both are ... -
Organising and Implementing Local Economic Development Initiatives at the District level in Ghana
Akudugu, Jonas Ayaribilla (2013-12-20)The term Local Economic Development (LED) is not is not new, but has an emerging context and usage. The contemporary local economic development approach is conceived as a development strategy that taps the synergy of ... -
Organization and function of signaling molecules in sperm
Hamzeh, Hussein (2017-09-15)Successful fertilization depends on the ability of sperm to locate the egg. Sperm from different species rely on diverse signaling components to gather chemical and physical cues and transduce them into a behavioral swimming ... -
Organization principles of thalamocortical input onto deep-layer inhibitory neurons of the barrel cortex
Messore, Luis Fernando (2024-02-28)Thalamus functions as the main route by which incoming sensory information reaches the cerebral cortex. Thalamic nuclei will receive input from the sensory receptors in the periphery and relay it to different areas in the ... -
Orientation and Search Strategies of Desert Arthropods: Path Integration Models and Experiments with Desert Ants, Cataglyphis fortis (Forel 1902)
Merkle, Tobias Friedrich Christian (2007)Path integration enables desert arthropods to find back to their nest on the shortest track from any position. To perform path integration successfully, speeds and turning angles along the preceding outbound path have to ... -
Orientation reversal of manifolds
Müllner, Daniel (2009-03-06)We study the phenomenon of chirality in the context of manifolds. An orientable manifold is called amphicheiral if it admits an orientation-reversing self-map and chiral if it does not. In addition to being continuous and ... -
El origen de la argolla peruana y la evolución de un discurso sobre la exclusión social
Nureña, César R. (2023)In Peru, the term argolla went from being just a way to designate an elite segment in the 19th century, to concentrate nowadays a vast range of meanings, referring to closed groups in any field, but also types of ... -
Origins of Endothermy in the Mammalian Lineage: the Evolutionary Beginning of Fibro-lamellar Bone in the “Mammal-Like” Reptiles
Shelton, Christen Don (2015-07-07)This study reports on long bone histology of the pelycosaurs, and proposes the hypothesis that the presence of fibro-lamellar bone (FLB) and high growth rates were already present in the basal most synapsids during the ... -
The orphan G protein-coupled receptor GPR17: its pharmacology and function in recombinant and primary cell expression systems
Simon, Katharina Anna Maria (2017-04-26)The reconstitution of myelin sheaths, so called remyelination, represents an innovative therapeutic goal in multiple sclerosis (MS), the most common inflammatory-demyelinating disease of the central nervous system (CNS). ... -
Orte der Muße und Repräsentation: Zu Ausstattung und Funktion römischer Loggien (1470–1527)
Allekotte, Jutta (2011-11-21)Eine Loggia ist nicht nur ein prägnantes architektonisches Merkmal oder ein geschützter und zugleich luftiger Raum, der einen schönen Ausblick bietet; sie ist darüber hinaus vor allem Ausdruck einer sublimierten Lebenskultur. ...