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Extracellular vesicles derived from Hepatitis-D Virus infected cells induce a proinflammatory cytokine response in human peripheral blood mononuclear cells and macrophages

Jung, Stephanie; Altstetter, Sebastian Maximilian; Wilsch, Florian; Shein, Mikhail; Schütz, Anne Kathrin; Protzer, Ulrike (2020-02-14)

Hepatitis D Virus (HDV) is a satellite virus requiring a Hepatitis B Virus (HBV) envelope proteins for productive infection. Hepatitis D is the most severe form of viral hepatitis and is a global health threat affecting ...

Mouse models of type I interferonopathies

Luca, Domnica; Kato, Hiroki (2024-12-16)

Type I interferonopathies are severe monogenic diseases caused by mutations that result in chronically upregulated production of type I interferon. They present with a broad variety of symptoms, the mechanisms of which are ...