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    • The SAVED domain of the type III CRISPR protease CalpL is a ring nuclease 

      Binder, Sophie G.; Schneberger, Niels; Schmitz, Maximilian; Engeser, Marianne; Geyer, Matthias; Rouillon, Christophe; Hagelueken, Gregor (2024-08-21)
      Prokaryotic CRISPR-Cas immune systems detect and cleave foreign nucleic acids. In type III CRISPR-Cas systems, the Cas10 subunit of the activated recognition complex synthesizes cyclic oligoadenylates (cOAs), second ...