E-Dissertationen: Browsing E-Dissertationen by Title
Now showing items 1958-1977 of 4089
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Investigations on 1,2-oxaphosphetane complexes
Kyri, Andreas Wolfgang (2017-11-27)In this thesis, first derivatives of previously unknown 1,2-oxaphosphetane complexes were synthesized, either by reaction of Li/Cl phosphinidenoid complexes with epoxides or by formal insertion into the OH bond of 2-iodoethanol ... -
Investigations on centrosomes, their function and regulation during immune synapse formation
Weier, Ann-Kathrin (2022-01-24)The centrosome is a cellular organelle well known for its function during cell division. It consists of two centrioles that are formed by microtubules and surrounded by a multiprotein matrix the so-called pericentriolar ... -
Investigations on Marine Natural Products from Indo-Pacific Nudibranchia (Mollusca: Gastropoda): Chemoecology, Medicinal Potential & Toxin Resistance
Hertzer, Cora (2022-03-22)This thesis focusses on the investigation of marine natural products (MNPs) from nudibranchs of the Central Indo-Pacific Ocean and their food sources. MNPs are important lead structures in the drug discovery process, as ... -
Investigations on structure and biosynthesis of ribosomal peptide natural products involved in a tripartite mutualistic interaction
Soto Zarazua, Maria Guadalupe (2024-04-16)(noch nicht zugänglich / not yet accessible) -
Investigations on the early biosynthetic steps of griseorhodin A
Eklund, Minna Leena (2012-05-03)Presented here are the results concerning the early biosynthesis of the telomerase inhibitor griseorhodin A.<br /> The griseorhodin biosynthetic gene cluster encodes components of a type II polyketide synthase (PKS). The ... -
Investigations on the structure, biosynthesis and biology of antibacterial cyclic lipopeptides
Schmidt, Yvonne (2013-03-21)The study was aimed to find new antibacterial cyclic lipopeptides in <i>Pseudomonas</i> bacteria using genome mining techniques. Application of this genome-driven approach led to the <i>in-silico</i> identification of ... -
Investigations on the synthesis and reactivity of σ3λ3-oxaphosphirane complexes with fluorinated C-substituents
Murcia García, Cristina (2017-03-02)The objective of this PhD work was to synthesize new oxaphosphirane complexes having the triphenylmethyl group bound to phosphorus. These derivatives may possess a higher lability of the P-C exocyclic bond than other ... -
Investigations to quantify individual exposure to solar ultraviolet erythemal radiation including cloud meteorological impact
Kelbch, Alexander (2020-07-09)Combined meteorological and dosimetric ultraviolet (UV) erythemal radiation (UVER) measurements were performed in 2016 and 2017. Based on collected data sets the actual UVER exposure of outdoor working probands is determined ... -
Involvement of autophagy in the metabolism of Amyloid Precursor Protein and effects of familial Alzheimer’s disease-associated mutations of Presenilin-1
Nguyễn, Thành Tiền (2014-12-01)Alzheimer’s disease (AD) is the most common form of neurodegenerative diseases, which is associated with extracellular deposits of the amyloid β-peptide (Aβ) and intraneuronal aggregates of hyperphosphorylated tau protein ... -
(Iodo)-Tellur-Polykationen und Trihalogenotelluriumionen in Salzen mit Halogeno(oxo)metallaten
Forge, Frank (2018-12-20)Die vorliegende Arbeit befasst sich mit der Darstellung von Tellur-Polykationen, TeX3<sup>+</sup> -Kationen und Iodo-Tellur-Polykationen mit Halogenido- oder Oxohalogenidometallaten als Anionen sowie einer neuen Modifikation ... -
Ionic liquids as novel reaction media for the chemical synthesis of peptides
Chen, Ming (2016-12-09)To seek the best solvent in which the peptide can dissolve is usually a serious challenge in peptide chemical synthesis. Ionic liquids, which are liquid below 100 °C, or even at room temperature, showed an outstanding ... -
Ionic Liquids in Dye Sensitized Solar Cells: Theoretical Assessment of Properties and Applications
Weber, Henry (2016-12-21)Dye-sensitized solar cells have the potential to play a major role in the future of the global energy economy. Unfortunately, they still lack the consistency and durability to be truly competitive from a commercial point ... -
Ionized and Photodissociation Regions toward a New Sample of Massive Star-forming Clumps
Kim, Wonju (2018-07-16)HII regions are an excellent indicator of high-mass star-forming regions and ongoing star formation in galaxies. Powerful outflows from O/B stars in their early stages and, during their whole life, intense UV radiation and ... -
Isogeometric Approximation of Variational Problems for Shells
Perl, Ricardo (2016-05-27)The interaction of applied geometry and numerical simulation is a growing field in the interplay of com- puter graphics, computational mechanics and applied mathematics known as isogeometric analysis. In this thesis we ... -
Isolation of secondary fungal metabolites and their influence on sphingolipid metabolism
Kralj, Ana (2007)Development of new drugs, especially in the area of oncological and infectious diseases, represents today one of the most important research fields. The marine environment is a tremendous source of natural products. Drug ... -
Isolierung und Strukturaufklärung von Xanthon-Derivaten, Anthrachinonen, Angucyclinen und anderen Sekundärmetaboliten aus terrestrischen und marinen Bakterien
El-Hachach, Katja (2008)In dieser Arbeit wurden marine und terrestrische Streptomyceten sowie Bakterien aus der Nordsee nach Auswahl aufgrund eines chemischen und biologischen Vorscreenings hinsichtlich ihres Sekundärmetabolitenspektrums genauer ... -
Isolierung von kleinen funktionalen Peptiden durch mRNA Display: Eine neue Klasse von Effektoren des humanen α-Thrombins
Raffler, Nikolai (2002)In der vorliegenden Arbeit wurde das mRNA Display zur Selektion von kleinen funktionalen Peptiden eingesetzt. Diese in vitro Selektionstechnik ermöglicht die kovalente Verknüpfung von Genotyp und Phänotyp eines Proteins. ... -
Isoprene Secondary Organic Aerosol in a Global Chemistry Climate Model
Stadtler, Scarlet (2018-09-26)Atmospheric aerosol influences the climate system, modifying atmospheric radiation directly and indirectly. Up to 90% to the total organic aerosol is formed through the oxidation of hydrocarbons and subsequent nucleation, ... -
Isotopes for fundamental research 83mKr for KATRIN and 101Rh and 109Cd for XRD studies on planets
Rasulbaev, Makhsud (2011-03-15)The feasibility of production of <sup>83</sup>Rb from liquid, natural Br at the Bonn Cyclotron was shown. Production of <sup>83</sup>Rb/<sup>83m</sup>Kr generators for KATRIN Collaboration was optimized. <sup>83m</sup>Kr ... -
The isotropy of the Universe as seen through galaxy clusters
Migkas, Konstantinos Nikolaos (2021-07-07)The cosmological principle (CP) postulates that the Universe is isotropic and homogeneous. This implies that the Universe has the same expansion rate toward every direction and holds similar amounts of matter when averaged ...