E-Dissertationen: Auflistung E-Dissertationen nach Titel
Anzeige der Dokumente 1697-1716 von 4077
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I) Characterization of LytR-CpsA-Psr enzymes and their role in Staphylococcus aureus cell wall formation
(2022-04-04)
II) Elucidating the mode of action of Cacaoidin, a novel class V lantibiotic Antibiotic resistance poses a serious threat to human health, demanding for the discovery and development of antibiotics with resistance-breaking properties. New antibiotics should be sought with the focus on novel chemistry ... -
Dnajc22 - a new susceptibility gene for salt-sensitive hypertension
(2015-06-10)Chaperones of the heat shock (HSP) 70 family mediate elementary funtions in a cell, such as folding, oligomerization, transport, or degradation of proteins. Their function is particularly needed when cells are exposed to ... -
In vitro Differentiation of Human Embryonic Stem Cells into Precursors of the Central Nervous System
(2006)Human embryonic stem cells with the property of pluripotency and unlimited selfrenewal are a promising tool for basic research and future transplantation strategies. Following the establishment of basic techniques of human ... -
In vitro Versuche zu den Wirkungen von Kupferverbindungen, Calciumhydroxid, Kaliumcarbonat und dem Alkylpolyglycosid Glucopon 215 CSUP auf Konidien und frühe Entwicklungsstadien von Venturia inaequalis
(2006)In der vorliegenden Arbeit wurden die Wirkungen verschiedener Kupferverbindungen sowie von Calciumhydroxid, Kaliumcarbonat und dem Alkylpolyglycosid Glucopon 215 CSUP auf Konidien und frühe Entwicklungsstadien des ... -
In vitro-Simulation der Funktion von Adhäsionsmolekülen im Prozess der hämatogenen Metastasierung von Tumorzellen und deren Inhibition durch Heparin
(2008)<p>Das Auftreten einer Metastasierung im Verlauf einer Krebserkrankung stellt die häufigste Todesursache für die meisten Patienten dar. Komplexe und zahlreiche Mechanismen vermitteln die Invasion von Zellen des Primärtumors ... -
Kitasatospora putterlickiae F18-98, ein neu isolierter Bakterienstamm aus der Rhizosphäre von Putterlickia verrucosa: Molekularbiologische und biochemische Untersuchungen zur Aminohydroxybenzoesäure-Biosynthese
(2003)Maytansinoide Naturstoffe sind potente Verbindungen mit antineoplastischer Aktivität, die aus Höheren Pflanzen, Bakterien und aus Moosen isoliert wurden. Die vorliegende Arbeit befasst sich mit dem biogenetischen Ursprung ... -
Paramecium biaurelia im niederfrequenten Magnetfeld: Auswirkungen auf das Schwimmverhalten, die cAMP-, cGMP- und 5`-Methoxytryptamin-Konzentrationen
(2001)<i>Paramecium biaurelia </i>wurde eingesetzt, um Effekte eines niederfrequenten Magnetfeldes (50 Hz) der Flußdichte 2 mT auf das Schwimmverhalten und die Signaltransduktion dieser Einzeller zu untersuchen. Modifikationen ... -
Identification and characterization of novel keratin associated proteins using a genetic interaction screening system
(2009-07-21)Keratins are an integral and important constituent of the epithelial cytoskeleton and protect epithelial cells against stress. In addition to their well-established function as cytoskeletal scaffolds in epithelia, recent ... -
Identification and characterization of novel ligands for purinergic P2X receptors
(2016-05-31)P2X receptors are ligand-gated ion channels activated by adenosine-5’-triphosphate (ATP). Seven different subtypes exist termed P2X1 - P2X7. P2X receptors exist as homo- or hetero-trimers. They show a ubiquitous expression, ... -
Identification and molecular characterisation of unknown genes involved in desiccation tolerance mechanisms in the resurrection plant Craterostigma plantagineum
(2014-11-06)The mechanisms that enable vegetative desiccation tolerance in the resurrection plant <i>Craterostigma plantagineum</i> are not fully understood. Recently, transcriptome data from this plant were obtained thus providing ... -
Identification and pharmacological characterization of nucleotide pyrophosphatase/phosphodiesterase-1 (NPP1) and -4 (NPP4) inhibitors
(2022-07-29)Ectonucleotidases are enzymes involved in different physiological functions and mainly in the regulation of purinergic signaling; in fact, they regulate the duration of purinergic receptor activation by catalyzing the ... -
Identification of a Novel Mycobacterial Gene Involved in the Synthesis of a Phenolic Glycolipid and its Role in the Prevention of Phagosome Maturation
(2007)Pathogenic Mycobacteria persist in an early endosome-like compartment by interfering with late endosomal fusion mediating factors. Studies have unraveled some of the mechanisms employed by mycobacteria to create a niche ... -
Identification of a putative Litomosoides sigmodontis phosphate permease, Ls-ppe-1, and its role in the interaction between filarial nematodes and their Wolbachia endosymbionts & Establishment of RNA interference in the rodent filaria Litomosoides sigmodontis, a model of human filariasis
(2009-12-09)Filariasis is a vector-borne disease that affects 200 million individuals in the tropics, a large number of them seriously, where the disease leads to blindness (onchocerciasis) or elephantiasis (lymphatic filariasis). The ... -
Identification of alpha-synuclein and ataxin-3 expression modifying compounds
(2024-02-16)(noch nicht zugänglich / not yet accessible) -
Identification of cisplatin resistance mechanisms and alternative treatment options for testicular germ cell tumors
(2023-06-21)Type II testicular germ cell tumors (TGCTs) are the most prevalent tumors in young men aged 18 to 35 years. TGCTs are classified as seminomas and non-seminomas. Embryonal carcinomas (EC), representing the cancer stem cell ... -
Identification of components and substrates of Snf1-related kinase 1 (SnRK1) complexes in Arabidopsis thaliana
(2019-04-04)Similarly to yeast Sucrose nonfermenting 1 (Snf1) and animal AMP-activated protein kinases (AMPKs), plant Snf1-related (SnRK1) kinases play a central role in the regulation of cellular energy homeostasis and responses to ... -
Identification of genetic factors involved in the regulation of stress
(2012-08-29)In this QTL mapping study, several genetic regions were linked to anxiety- and depression-related behavior in the mouse. Furthermore, some previously identified QTL linked to these behavioral traits were verified in the ... -
Identification of Genetic Risk Variants for the Development of Gastric Adenocarcinoma
(2023-03-07)Gastric cancer (GC) is a clinically heterogeneous and one of the most common malignant tumour entities affecting the human gastrointestinal tract with a multifactorial aetiology. Beside environmental risk factors, also ... -
Identification of Genomic Alterations in Castration Resistant Prostate Cancer using Next Generation Sequencing
(2014-01-03)Castration resistant prostate cancer (CRPC) is the most aggressive form of prostate cancer (PCa). For the development of novel therapeutic targets for CRPC, it is key to decipher the molecular alterations underlying this ... -
Identification of hadronic τ decays using the τ lepton flight path and reconstruction and identification of jets with a low transverse energy at intermediate luminosities with an application to the search for the Higgs boson in vector boson fusion with the ATLAS experiment at the LHC
(2010-07-01)Three studies of different components of the object reconstruction with the ATLAS experiment using simulated data are presented. In each study, a method for the improvement of the reconstruction is developed and the ...
