E-Dissertationen: Browsing E-Dissertationen by Subject "G protein-coupled receptor"
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Elucidating agonist-induced signaling patterns of human G protein-coupled receptor GPR17 and uncovering pranlukast as a biased mixed agonist-antagonist at GPR17
Hennen, Stephanie Monika (2011-11-15)The progress of human genome sequencing has revealed the existence of several hundred orphan G protein-coupled receptors (GPCRs), whose endogenous ligands are not yet identified, thus their deorphanization and characterization ... -
Identification, optimization and characterization of pharmacological tools for the cannabinoidactivated orphan G protein-coupled receptor GPR18 and related receptors
Schoeder, Clara Tabea (2017-12-21)Cannabinoid receptors comprise two classical subtypes, CB<sub>1</sub> and CB<sub>2</sub>, which belong to the large family of G protein-coupled receptors (GPCRs). They are the major targets of cannabinoids such as ...