E-Dissertationen: Auflistung E-Dissertationen nach Schlagwort "T-Zelle"
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Characterization of the role of Hydroxyprostaglandin dehydrogenase 15-(NAD) in human regulatory T cells
Schönfeld, Eva Alexandra (2012-06-14)The focus of the present study was the characterization of the hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD) in CD4+CD25+ regulatory T cells (Treg) concerning its regulation and role for the development and suppressive ... -
The mannose receptor influences antigen-presenting cells by direct interaction with CD45R0
Embgenbroich, Maria Katharina (2017-05-15)The immune system has to manage the critical decision to induce either immunity or tolerance. Cells that take part in the regulatory processes of the immune system are amongst others antigen presenting cells (APCs), ... -
Molekulare Mechanismen der Kreuzpräsentation
Gottschalk, Catherine (2013-06-14)Ein Schlüsselwerkzeug zur Aktivierung und Tolerisierung zytotoxischer CD8<sup>+</sup> T-Zellen ist die Kreuzpräsentation. Die Aufklärung zellulärer und molekularer Mechanismen der Kreuzpräsentation und ihrer Folgen ist ... -
Novel aspects of TGFβ in human CD4+ T cell biology
Claßen, Sabine (2008)During this thesis, several novel aspects of TGFß in human CD4<sup>+</sup> T cell biology were investigated. First, we were interested, which factors control the resting state of CD4<sup>+</sup> T cells. Genome-wide ... -
Understanding the role of SATB1 in CD4+ T cells by analysis of conditionally targeted mice generated by genetic engineering
Sommer, Daniel (2018-12-12)Special-AT-rich-binding protein 1 (SATB1) is a nuclear protein providing higher order chromatin organization and regulation of gene expression, especially in T cells. In regulatory T cells, SATB1 is repressed to maintain ...