The Faculty of Mathematics and Natural Sciences: E-Dissertationen
Recent Submissions
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Synthesis and Characterization of New Amphiphilic And Chiral Squaraines
(2025-11-12)Squaraines are a class of dye molecules obtained through reaction of mostly electron-rich molecules with squaric acid. It is an intriguing class of molecules, which has a wide field of applications and seemingly endless ... -
Total synthesis of Epicoccolide A & B and two related analogs
(2025-11-12)The family of epicoccolides has been known for over a decade now and show remarkable biological properties in a variety of fields. Different groups have reported antibacterial, antifungal and antitumor reactivity. More ... -
Unified Total Synthesis of Lysolipin Natural Products: Methodology and Bioactivity behind Polycyclic Aromatic Compounds
(2025-11-12)Lysolipin natural products are a family of bacterial polycyclic xanthones, renowned for their antibiotic potency and structural diversity. Yet, their complex architectures have long eluded synthetic access, and their ... -
Untersuchung zur mikrobiellen Produktion, Aufreinigung und Toxizität potenzieller Zuckerersatzstoffe
(2025-11-12)(noch nicht zugänglich / not yet accessible) -
Ingestion of micro- and nanoplastic perturbs tissue homeostasis and macrophage core functions
(2025-11-07)Plastic pollution has emerged as a global environmental crisis of unprecedented scale. Micro- and nanoplastic (MNP) pervade ecosystems, resulting in persistent exposure for all living organisms, including humans. MNP have ... -
Quantenchemische Berechnungen der Sauerstoffentwicklungsreaktion auf beschichteten Titandioxidoberflächen
(2025-11-07)In dieser Arbeit wurde mittels quantenchemischer Methoden nach alternativen Materialien als Katalysatoren für die Sauerstoffentwicklungsreaktion (OER) gesucht. Substituiertes Rutil-TiO<sub>2</sub> mit und ohne Monolagen- ... -
The impact of mechanical stretch on the stability of desmosomes in epithelia
(2025-11-07)The mechanoresponse of epithelia is a well-known and essential process. Both cytoskeleton and cell adhesion sites react to mechanical stimuli, e.g. mechanical stretch. Cell adhesions like desmosomes act as connection sites ... -
Influence of Cross Linking on the Stability of Functional Emulsion-Derived Polymer Films
(2025-11-04)(noch nicht zugänglich / not yet accessible) -
Data-Driven Strategies in Neurodegenerative Diseases: Advancing Drug Development and Disease Management
(2025-11-04)Neurodegenerative Disorders, including Alzheimer's, Parkinson's, and Huntington's Disease, pose major challenges to modern medicine due to their progressive nature and impact on patients and the healthcare system. These ... -
A Design Study for an Experiment to Search for Dark Photons at ELSA
(2025-11-03)This thesis presents a design study for proposed dark photon search experiment at the Electron Stretcher Accelerator ELSA in Bonn, called <span style="font-variant: small-caps;">Lohengrin</span>.<br/> Different proposed ... -
Hardware-Aware Quantum Optimization
(2025-11-03)Quantum Optimization (QO) is emerging as a promising approach to tackle hard combinatorial optimization problems by leveraging the unique computational properties of quantum hardware. In recent years, QO has gained traction ... -
Hydrogen Millimeter Recombination Lines as a Tracer of Extragalactic Star Formation Rates
(2025-11-03)When studying the structure and evolution of distant galaxies, the total star formation rate (SFR) of a given galaxy is an important observable. It is related to the gas, dust, and stellar mass content of a galaxy, and is ... -
Analysen zu intrazellulären Bakterien im Kontext des One-Health-Ansatzes
(2025-10-31)In dieser Dissertation wurden intrazelluläre bakterielle Erreger in Bezug auf deren Ausbreitung, antibiotische Therapie und Biologie untersucht. Der erste Teil der Arbeit befasste sich mit zoonotischen sowie neuartigen ... -
Structure and functional characterization of the B-domain and the full-length coagulation factor VIII
(2025-10-29)Factor VIII (FVIII) is a large glycoprotein that serves as a non-enzymatic cofactor for activated Factor IX, facilitating the proteolytic activation of Factor X in the coagulation cascade. Deficiency of FVIII leads to ... -
Periplectic and Isomeric Lie superalgebras, KLR algebras and Categorification
(2025-10-29)We explore the finite dimensional representation theory of the periplectic Lie superalgebra and the isomeric Lie superalgebr, focusing on explicit descriptions of their projective generators' endomorphism rings. Using ... -
Development of intracellular ligands and targeted protein degraders for chemokine receptors and histone deacetylases
(2025-10-29)Chemokine receptors are a subfamily of G protein-coupled receptors (GPCRs) that play a crucial role in the immune system by regulating the migration and positioning of immune cells. They are involved in various physiological ... -
Investigation of BRD9 inhibition as alternative treatment option for testicular germ cell tumors
(2025-10-29)Type II germ cell tumors are the most prevalent tumor in young men between the ages of 15 and 35 years. They arise from a block in primordial germ cell differentiation leading to a precursor lesion called germ cell neoplasia ... -
Improvement of Streamflow Forecasting for Flood Management and Mitigation in the White Volta Basin, Northern Ghana
(2025-10-24)Flooding in Ghana's White Volta basin has led to severe human displacement, fatalities, and extensive property damage. The region's heavy dependence on agriculture exacerbates these impacts, posing significant threats to ... -
Antibiotic-induced cellular effects in Wolbachia: Insights from cell wall biosynthesis inhibitors and corallopyronin A
(2025-10-24)(noch nicht zugänglich / not yet accessible) -
Pulsar timing and gravitational waves
(2025-10-23)Pulsars are magnetized rotating neutron stars that formed from the collapsed core of a massive star following a supernova. Charged particles are accelerated along the magnetic field lines producing electromagnetic radiation. ...
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