The Faculty of Medicine: Browsing Medizinische Fakultät by Resource Type "doc-type:article"
Now showing items 21-37 of 37
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Mini Review: Forensic Value of Aquaporines
Prangenberg, Julian; Doberentz, Elke; Madea, Burkhard (2021-12-17)Forensic pathologists are routinely confronted with unclear causes of death or findings. In some scenarios, it can be difficult to answer the specific questions posed by criminal investigators or prosecutors. Such scenarios ... -
Mini Review: The Forensic Value of Heat Shock Proteins
Prangenberg, Julian; Doberentz, Elke; Mawick, Anthea; Madea, Burkhard (2022-01-10)Forensic pathologists are routinely confronted with unclear causes of death or related findings. In some instances, difficulties arise in relation to questions posed by criminal investigators or prosecutors. Such scenarios ... -
Misfit of Complete Maxillary Dentures’ Posterior Palatal Seal following Polymerisation with Four Different Autopolymerising Resins: An In Vitro Study
Schiller, Simone; Rustemeier, Elke; Kraus, Dominik; Stark, Helmut; Müller, Frauke; Utz, Karl-Heinz (2022-07-30)Background: The majority of complete dentures are still conventionally manufactured using a flask-and-pack technique. However, the polymerization process may introduce a distortion of the denture body. The aim of this study ... -
Multimodal Virtual Reality-Based Assessment of Adult ADHD: A Feasibility Study in Healthy Subjects
Wiebe, Annika; Kannen, Kyra; Li, Mengtong; Aslan, Behrem; Anders, David; Selaskowski, Benjamin; Ettinger, Ulrich; Lux, Silke; Philipsen, Alexandra; Braun, Niclas (2022-04-18)Neuropsychological assessments are often surprisingly inaccurate in mapping clinically-reported attention-deficit hyperactivity disorder (ADHD) symptoms, presumably due to their low ecological validity. Virtual ... -
Neural Correlates of Smooth Pursuit Eye Movements in Schizotypy and Recent Onset Psychosis: A Multivariate Pattern Classification Approach
Schröder, Rebekka; Faiola, Eliana; Urquijo, Maria Fernanda; Bey, Katharina; Meyhöfer, Inga; Steffens, Maria; Kasparbauer, Anna-Maria; Ruef, Anne; Högenauer, Hanna; Hurlemann, René; Kambeitz, Joseph; Philipsen, Alexandra; Wagner, Michael; Koutsouleris, Nikolaos; Ettinger, Ulrich (2022-06-03)Schizotypy refers to a set of personality traits that bear resemblance, at subclinical level, to psychosis. Despite evidence of similarity at multiple levels of analysis, direct comparisons of schizotypy and clinical ... -
P300 Modulation via Transcranial Alternating Current Stimulation in Adult Attention-Deficit/Hyperactivity Disorder: A Crossover Study
Kannen, Kyra; Aslan, Behrem; Boetzel, Cindy; Herrmann, Christoph; Lux, Silke; Rosen, Helena; Selaskowski, Benjamin; Wiebe, Annika; Philipsen, Alexandra; Braun, Niclas (2022-07-18)Objective: A repeated finding regarding event-related potentials (ERPs) is that patients with ADHD show a reduced P300 amplitude. This raises the question of whether the attention of ADHD patients can be increased by ... -
Parameters Associated with the Required Drug Dose of Intravenous Immunoglobulin in Stable Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Feyen, Ludger; Schaub, Christina; Zimmermann, Julian; Nitsch, Louisa (2023-03-10)Background: Intravenous immunoglobulin (IVIg) is efficient and one of very few treatment options for patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). However, finding the optimal dose of ... -
Primary cilia and their effects on immune cell functions and metabolism: a model
Picon-Galindo, Ernesto; Latz, Eicke; Wachten, Dagmar (2022-05)Primary cilia are hair-like protrusions of the plasma membrane that function as cellular antennae and are present on most cells in the human body. Primary cilia dysfunction leads to severe diseases, commonly termed ... -
Pulmonary Arteriovenous Pressure Gradient and Time-Averaged Mean Velocity of Small Pulmonary Arteries Can Serve as Sensitive Biomarkers in the Diagnosis of Pulmonary Arterial Hypertension: A Preclinical Study by 4D-Flow MRI
Nahardani, Ali; Leistikow, Simon; Grün, Katja; Krämer, Martin; Herrmann, Karl-Heinz; Schrepper, Andrea; Jung, Christian; Moradi, Sara; Schulze, Paul Christian; Linsen, Lars; Reichenbach, Jürgen R.; Hoerr, Verena; Franz, Marcus (2021-12-28)(1) Background: Pulmonary arterial hypertension (PAH) is a serious condition that is associated with many cardiopulmonary diseases. Invasive right heart catheterization (RHC) is currently the only method for the definitive ... -
Reliability of Retinal Layer Annotation with a Novel, High-Resolution Optical Coherence Tomography Device: A Comparative Study
von der Emde, Leon; Saßmannshausen, Marlene; Morelle, Olivier; Rennen, Geena; Holz, Frank; Wintergerst, Maximilian; Ach, Thomas (2023-03-31)Optical coherence tomography (OCT) enables in vivo diagnostics of individual retinal layers in the living human eye. However, improved imaging resolution could aid diagnosis and monitoring of retinal diseases and identify ... -
Second-line and third-line therapy with nanoliposomal irinotecan (nal-IRI) in pancreatic cancer: a single-center experience and review of literature
Möhring, Christian; Frontado Graffe, Freddy José; Bartels, Alexandra; Sadeghlar, Farsaneh; Zhou, Taotao; Mahn, Robert; Marinova, Milka; Feldmann, Georg; Brossart, Peter; Glowka, Tim; Kalff, Jörg; Strassburg, Christian; Gonzalez-Carmona, Maria (2023-02-15)Background: Prognosis of patients with pancreatic cancer is still extremely poor. First-line palliative therapies with FOLFIRINOX or gemcitabine/nab-paclitaxel have been established in the last decade. In the second-line, ... -
Shedding light on the role of cAMP in mammalian sperm physiology
Balbach, Melanie; Beckert, Vera; Hansen, Jan N.; Wachten, Dagmar (2018-06-15)Mammalian fertilization relies on sperm finding the egg and penetrating the egg vestments. All steps in a sperm's lifetime crucially rely on changes in the second messenger cAMP (cyclic adenosine monophosphate). In recent ... -
Small Changes in Patient Arrival and Consultation Times Have Large Effects on Patients' Waiting Times: Simulation Analyses for Primary Care
Grot, Matthias; Kugai, Simon; Degen, Lukas; Wiemer, Isabel; Werners, Brigitte; Weltermann, Birgitta (2023-01-18)(1) Background: Workflows are a daily challenge in general practices. The desired smooth work processes and patient flows are not easy to achieve. This study uses an operational research approach to illustrate the general ... -
Sympathetic Innervation Modulates Mucosal Immune Homeostasis and Epithelial Host Defense
Mallesh, Shilpashree; Ten Hove, Anne S.; Schneider, Reiner; Schneiker, Bianca; Efferz, Patrik; Kalff, Jörg C.; de Jonge, Wouter J.; Wehner, Sven (2022-08-21)Intestinal mucosal cells, such as resident macrophages and epithelial cells, express adrenergic receptors and are receptive to norepinephrine, the primary neurotransmitter of the sympathetic nervous system (SNS). It has ... -
UDP-glucuronosyltransferase polymorphisms affect diethylnitrosamine-induced carcinogenesis in humanized transgenic mice
Landerer, Steffen; Kalthoff, Sandra; Paulusch, Stefan; Strassburg, Christian P. (2020-08-28)UDP-glucuronosyltransferase (UGT) 1A enzymes detoxify a broad array of exogenous compounds including environmental toxins and carcinogens. Case-control studies identified genetic variations in UGT1A genes leading to reduced ... -
Virtual reality in the diagnostic and therapy for mental disorders: A systematic review
Wiebe, Annika; Kannen, Kyra; Selaskowski, Benjamin; Mehren, Aylin; Thöne, Ann-Kathrin; Pramme, Lisa; Blumenthal, Nike; Li, Mengtong; Asché, Laura; Jonas, Stephan; Bey, Katharina; Schulze, Marcel; Steffens, Maria; Pensel, Max Christian; Guth, Matthias; Rohlfsen, Felicia; Ekhlas, Mogda; Lügering, Helena; Fileccia, Helena; Pakos, Julian; Lux, Silke; Philipsen, Alexandra; Braun, Niclas (2022-10-30)Background: Virtual reality (VR) technologies are playing an increasingly important role in the diagnostics and treatment of mental disorders. Objective: To systematically review the current evidence regarding the use ... -
X-linked variations in SHROOM4 are implicated in congenital anomalies of the urinary tract and the anorectal, cardiovascular and central nervous systems
Kolvenbach, Caroline; Felger, Tim; Schierbaum, Luca; Thiffault, Isabelle; Pastinen, Tomi; Szczepańska, Maria; Zaniew, Marcin; Adamczyk, Piotr; Bayat, Allan; Yilmaz, Öznur; Lindenberg, Tobias; Thiele, Holger; Hildebrandt, Friedhelm; Hinderhofer, Katrin; Moog, Ute; Hilger, Alina; Sullivan, Bonnie; Bartik, Lauren; Gnyś, Piotr; Grote, Phillip; Odermatt, Benjamin; Reutter, Heiko; Dworschak, Gabriel (2022-11-15)Background: SHROOM4 is thought to play an important role in cytoskeletal modification and development of the early nervous system. Previously, single-nucleotide variants (SNVs) or copy number variations (CNVs) in SHROOM4 ...