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Pilzkontaminationen in Korneatransplantaten: Effektivität antimykotischer Medienzusätze und Anwendbarkeit molekularbiologischer Detektionsmethoden
(2023-10-16)
Postoperative Infektionen stellen eine schwerwiegende Komplikationen nach Korneatransplantation dar. In den letzten Jahren wurde ein Anstieg der Inzidenz von Pilzinfektionen nach Keratoplastik festgestellt. Aktuell werden ...
Impact of aging and enriched environment on α-synuclein propagation
(2022-04-06)
Parkinson's disease (PD) is the second most common neurodegenerative disease. The prevalence of sporadic PD results from a complex interaction of demographic, genetic, and environmental factors. Age is one of the strongest ...
Protein markers of inflammation and ageing in a European multi-centre dementia cohort
(2024-03-01)
Inflammation plays a key role in Alzheimerʼs disease (AD) progression. Microglia in the AD brain are exposed to pathological amyloid β (Aβ42) and tau peptide aggregates, resulting in the NLRP3 inflammasome activation ...
Role of TLR2 in immune sensing of gut microbiota in RNA virus induced glomerulonephritis
(2024-05-22)
Chronically infected patients with human immune deficiency virus (HIV) are at high risk of developing autoimmune diseases. Despite successful anti-retroviral therapy, autoimmune diseases and renal diseases affect 10–15 % ...
Role of IFN‑γ induced genes in cell autonomous defence against Legionellae
(2022-05-27)
L. pneumophila and L. longbeachae are ubiquitous environmental bacteria that can cause a severe pneumonia, known as Legionnaires’ Disease, when contaminated aerosols are inhaled by susceptible humans. During ......