The Faculty of Mathematics and Natural Sciences: Search
Now showing items 1151-1160 of 1161
Ectopic expression of transcription factors to overcome the lineage barrier between embryonic stem cells and trophoblast stem cells in mouse and human
(2023-04-19)
The placenta is a transient organ that exhibits various essential functions during pregnancy that allow for proper development of the embryo. Placenta and embryo originate from the first lineage separation in mammalian ...
The Immune Memory Response and Metabolic Requirements of Human Gamma Delta T Cells
(2024-05-14)
γδ T cells are unconventional T cells that can mediate pro-inflammatory, cytotoxic, phagocytotic and professional antigen presenting properties. Sharing the features of both adaptive and innate immunity, γδ T cells also ...
Human iPSC-derived in vitro models of the peripheral nervous system for cellular pain and somatosensation research
(2022-01-07)
The term 'somatosensation' summarizes the sensation of touch, body position, temperature and pain experienced by animals or humans. Peripheral sensory neurons can be classified according to their primary sensation as ...
Activation Mechanisms of RIG-I
(2020-11-02)
(noch nicht zugänglich / not yet accessible)
Funktion des Eisen-Schwefelflavoproteins DsrL im dissimilatorischen Schwefelstoffwechsel
(2024-05-21)
Das FeS-Cluster enthaltende Flavoprotein DsrL besitzt NAD(P)H-Oxidoreduktase-Aktivität und dient als Elektronendonor oder -akzeptor für die von DsrAB katalysierte Reaktion während der dissimilatorischen Sulfat/Sulfit-Reduktion ...
The yeast prion domain Sup35 NM models features of human neurodegenerative diseases in vivo
(2024-05-21)
In neurodegenerative diseases, such as prion diseases and Alzheimer’s disease, disease- associated proteins misfold and form amyloid deposits that progressively invade the CNS, leading to severe neurodegeneration. Accumulating ...
G protein-coupled receptors mobilize intracellular calcium via the Gs-βγ-PLCβ module
(2024-05-22)
(noch nicht zugänglich / not yet accessible)
Alzheimer’s and inflammation: exploring the interplay between immune cells in the peripheral immune system and the central nervous system through single-cell RNA-seq
(2024-05-23)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease that is the most common cause of dementia and the sixth leading cause of death globally (Haque & Levey, 2019; World Health Organization, 2017). Increases ...
Engagement of NKT cells during cross-priming enhances the CD8+ T cell response via GATA3 and IL-4/TNFα
(2022-04-21)
(noch nicht zugänglich / not yet accessible)