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Sympathetic Innervation Modulates Mucosal Immune Homeostasis and Epithelial Host Defense
(2022-08-21)
Intestinal mucosal cells, such as resident macrophages and epithelial cells, express adrenergic
receptors and are receptive to norepinephrine, the primary neurotransmitter of the sympathetic
nervous system (SNS). It has ...
Reliability of Retinal Layer Annotation with a Novel, High-Resolution Optical Coherence Tomography Device: A Comparative Study
(2023-03-31)
Optical coherence tomography (OCT) enables in vivo diagnostics of individual retinal
layers in the living human eye. However, improved imaging resolution could aid diagnosis and
monitoring of retinal diseases and identify ...
Parameters Associated with the Required Drug Dose of Intravenous Immunoglobulin in Stable Chronic Inflammatory Demyelinating Polyradiculoneuropathy
(2023-03-10)
Background: Intravenous immunoglobulin (IVIg) is efficient and one of very few treatment
options for patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).
However, finding the optimal dose of ...
Additive prognostic impact of the cerebrospinal fluid arginine/ornithine ratio to established clinical scores in aneurysmal subarachnoid hemorrhage
(2023-04-14)
Cerebrospinal fluid (CSF) metabolites are increasingly recognized as prognostic
factors in aneurysmal subarachnoid hemorrhage (SAH). The CSF arginine/
ornithine ratio (Arg/Orn) was shown to predict cerebral vasospasms ...
Misfit of Complete Maxillary Dentures’ Posterior Palatal Seal following Polymerisation with Four Different Autopolymerising Resins: An In Vitro Study
(2022-07-30)
Background: The majority of complete dentures are still conventionally manufactured using a flask-and-pack technique. However, the polymerization process may introduce a distortion of the denture body. The aim of this study ...
Cost-effectiveness and Quality of Specialized and Routine Care in a German Cohort of Patients with Chronic Pruritus
(2023-04-21)
Chronic pruritus is a prevalent interdisciplinary symptom with a strong influence on health-related quality of life. Patients need extensive diagnostics and long-term treatment. This retrospective and prospective cohort ...
The DEAH helicase DHX36 and its role in G-quadruplex-dependent processes
(2020-10-12)
DHX36 is a member of the DExD/H box helicasefamily, which comprises a large number of proteinsinvolved in various cellular functions. Recently, thefunction of DHX36 in the regulation of G-quadruplexes(G4s) was demonstrated. ......
Detecting G4 unwinding
(2022-04-18)
DNA can, in addition to the B-DNA conformation, fold into a variety of additional conformations. Among them are G-quadruplex structures that have gained a lot of attention in recent years. G-quadruplex structures (G4s) are ...
Cytokine Production of CD56bright Natural Killer Cells From Human Immunodeficiency Virus–Infected Individuals Under Effective Antiretroviral Therapy
(2022-09-01)
Human immunodeficiency virus (HIV) infection is associated with impaired natural killer (NK) cell activity, which is only incompletely restored under antiretroviral therapy. Analyzing the bioenergetics profiles of oxygen ...