Institut für Klinische Chemie und Klinische Pharmakologie

 

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  • NIS-Seq enables cell-type-agnostic optical perturbation screening 

    Fandrey, Caroline I.; Jentzsch, Marius; Konopka, Peter; Hoch, Alexander; Blumenstock, Katja; Zackria, Afraa; Maasewerd, Salie; Lovotti, Marta; Lapp, Dorothee J.; Gohr, Florian N.; Suwara, Piotr; Świeżewski, Jędrzej; Rossnagel, Lukas; Gobs, Fabienne; Cristodaro, Maia; Muhandes, Lina; Behrendt, Rayk; Lam, Martin C.; Walgenbach, Klaus J.; Bald, Tobias; Schmidt, Florian I.; Latz, Eicke; Schmid-Burg, Jonathan L. (2024-12-19)
    Optical pooled screening offers a broader-scale alternative to enrichment-based perturbation screening, using fluorescence microscopy to correlate phenotypes and perturbations across single cells. Previous methods work ...

  • Enemy or ally? Fasting as an essential regulator of immune responses 

    Wilhelm, Christoph; Surendar, Jayagopi; Karagiannis, Fotios (2021-04-14)
    Nutrition is essential for supplying an organism with sufficient energy to maintain its bodily functions. Apart from serving as an energy supply, the immunomodulatory effects of diet are emerging as a central aspect of ...

  • Innate lymphoid cells - key immune integrators of overall body homeostasis: ILC – key immune integrators of overall body homeostasis 

    Karagiannis, Fotios; Wilhelm, Christoph (2018-06-04)
    The maintenance of the tissue barrier is essential to protect the host from external pathogens, thus ensuring the survival of the organism. This process requires the integration of various physiological signals originating ...