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Analysis of human T lymphocyte-derived immune responses against Staphylococcus aureus by delivery of in vitro transcribed antigens
Uebele, Julia (2016-07-06)Staphylococcus aureus is a harmless commensal of the human mucosa and at the same time the main cause of life-threatening nosocomial infections worldwide. In particular, the growing number of methicillin-resistant S. aureus ... -
Analysis of inclusive semileptonic B meson decays with τ lepton final states at the Belle experiment
Hasenbusch, Jan (2018-06-15)In this thesis, the measurement of the inclusive branching fraction of B→Xτν decays at the Belle experiment is presented. Previous measurements of the inclusive semileptonic b-hadron branching fraction BR(b→Xτν) in ... -
Analysis of Land Surface Dynamics in Ukraine Observed by Satellite Sensors
Ghazaryan, Gohar (2020-06-18)Land surface changes, induced by anthropogenic or climatic drivers, can dramatically impact ecosystem functioning. The growing amount of data from remote sensing and complementary data sources greatly supports the ... -
Analysis of lipid uptake and processing in cultured cells = Lipid-Aufnahme und Stoffwechsel in kultivierten Zellen
Hameed, Radwan Mohammed Ali (2013-01-28)To characterize lipid uptake pathways in cultured cells, uptake and metabolism of different isotope-labeled lipid probes were investigated in human skin fibroblasts, a mouse macrophage-like cell line (RAW264.7), human ... -
Analysis of martensitic microstructures in shape-memory-alloys: A low volume-fraction limit
Diermeier, Johannes (2016-11-28)In this work, we study the limiting behavior of a variational model which arises in the analysis of microstructures at austenite-martensite interfaces in shape-memory alloys. We consider an energy containing an elastic ... -
Analysis of Multitarget Activities and Assay Interference Characteristics of Pharmaceutically Relevant Compounds
Jasial, Swarit (2019-05-29)The availability of large amounts of data in public repositories provide a useful source of knowledge in the field of drug discovery. Given the increasing sizes of compound databases and volumes of activity data, computational ... -
Analysis of parasite-specific T cells and cellular interactions in the spleen during Plasmodium berghei induced experimental cerebral malaria
Schmidt, Kim Ellen (2011-12-12)Vector-transmitted parasitic infections are a global health problem. Diseases such as malaria are a major health threat and economic burden for developing countries. In Sub-Saharan Africa malaria causing Plasmodium ... -
Analysis of pixel systematics and space point reconstruction with DEPFET PXD5 matrices using high energy beam test data
Reuen, Lars (2011-03-04)To answer the current questions in particle physics vertex-detectors, the innermost sub-detector system of a multipurpose particle detector, with brilliant spatial resolution and at the same time with as little sensor ... -
Analysis of plant sterols and oxysterols in the serum of patients with sitosterolemia under different drug treatments
Khalf, Abdurraouf (2007)Sitosterolemia is a very rare inherited disease, characterized biochemically by elevated plasma levels of plant sterols and moderatly increase in the level of cholesterol and clinically by premature atherosclerosis due to ... -
Analysis of Random Fragment Profiles for the Detection of Structure-Activity Relationships
Batista, José (2008)Substructure- or fragment-type descriptors are effective and widely used tools for chemical similarity searching and other applications in chemoinformatics and computer-aided drug discovery. Therefore, a large number of ... -
Analysis of reprogramming-associated alterations using an isogenic human stem cell system
Haubenreich, Carolin (2022-03-04)Human induced pluripotent stem cells (iPSCs) could provide a valuable tool for the production of specific somatic cell types for disease modeling or cell replacement. Considering the molecular complexity of the reprogramming ... -
Analysis of SCF+ cardiac cells in mice
Hu, Tianyuan (2018-08-28)Proper regulation of c-kit receptor tyrosine kinase by its ligand, Stem Cell Factor (SCF), is essential for survival, growth, migration and differentiation of many types of stem/progenitor cells. However, its role in the ... -
Analysis of the AtMRS2 magnesium transporter family in Arabidopsis thaliana via gene-GFP fusions, heterologous complementations, and protein interaction studies
Weyand, Katrin (2007)Magnesium is unique in its chemical properties compared to the other biologically relevant cations. It plays an important role in many biological functions, e.g. as a cofactor for numerous enzymes, as the central atom of ... -
Analysis of the genetic potential of the spongederived fungus Penicillium chrysogenum E01-10/3 for polyketide production
Avramović, Marija (2011-03-14)The main goal of the presented dissertation was to evaluate the genetic potential of P. chrysogenum E01-10/3 strain for the production of polyketides.
This marine-derived P. chrysogenum strain was isolated from the ... -
Analysis of the Higgs boson decay in the H → τhadτhad channel and CP properties with √s = 13 TeV collisions at the ATLAS detector
Yuen, Stephanie P. Y. (2019-11-08)In 2012, the last unobserved particle predicted by the Standard Model of particle physics (SM), the Higgs boson, was discovered by the ATLAS and CMS collaborations in a number of its bosonic decay channels. This has been ... -
Analysis of the MBO scheme: from materials science to data clustering
Lelmi, Jona (2023-06-15)The Merriman, Bence, and Osher (MBO) scheme -- also known as thresholding scheme -- is a numerical method originally introduced to approximate the evolution by mean curvature flow (MCF). The algorithm produces a time ... -
Analysis of the Mechanical Reaction of Human Endothelial Cells to a Single Constant or Transient Uniaxial Strain
Santybayeva, Zhanna (2014-03-07)Many adherent cell types are continually exposed to a variety of mechanical stresses. For instance, vascular endothelial cells, alveolar cells, and cells of gastrointestinal tract experience periodic strains due to blood ... -
Analysis of the natural product biosynthesis in gliding bacteria using in vitro assays
Mir Mohseni, Mahsa (2017-01-10)Natural products are most important in drug discovery and therapy, e.g. more than 80% of antibiotics are derived from microorganisms. Antimicrobial resistance is a global threat and thus an urgent need for new antimicrobial ... -
Analysis of the physiological response of perivascular adipose tissue during cold exposure
Freyter, Benjamin M. (2023-02-22)Aortic valve disease (AVD) is common for people over 65 and its severity increases with age. Aortic aneurysm (AA) is the tenth cause of death for men above 55. Its prevalence was estimated to be up to 8.9% for men and up ... -
Analysis of the regulatory function of amino acids on metabolic targets and serotonin production in Drosophila melanogaster
Hübner, Tatjana (2016-08-09)Amino acid sensing mediates metabolic and behavioural adjustments in response to organismal needs. Several pathways are believed to be involved in amino acid sensing, including the TOR (Target of Rapamycin) pathway. However, ...