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The long noncoding RNA HIF1a-AS1 regulates endothelial cell function and is increased in patients with aortic valve disease and coronary artery disease
Zhou, Ling (2023-12-15)Long noncoding RNA HIF1a-AS1 is significantly dysregulated in different CVDs. However, the specific function and the mode of action of the HIF1a-AS1 are still poorly investigated in CVD. Here, we sought to explore the ... -
Long-term effects of childhood work on human capital formation, migration decisions, and earnings in rural Ethiopia
Mussa, Essa Chanie (2018-10-16)In Ethiopia, a quarter of children are child laborers, of which one in every three works full-time. Currently, more children than ever before also combine schooling with work. In addition, although net primary school ... -
Long-term timing of pulsars in globular clusters
Ridolfi, Alessandro (2017-12-20)Pulsars are fast rotating, magnetized neutron stars that result from the supernova explosion of massive stars. Thanks to their coherent radiation, emitted in the form of collimated beams from the two magnetic poles, pulsars ... -
Long-timescale atomistic simulations
Bulin, Johannes (2021-03-31)The simulation and analysis of particle systems dynamics is an important subfield of computational materials science. It allows the investigation of many properties of interest, such as reaction mechanisms, diffusion rates, ... -
Longitudinale funktionelle MRT Bildgebungsstudie zur Untersuchung der Auswirkungen eines forcierten Sporttrainings auf die zentrale Schmerzverarbeitung
Othman, Ahmed Emtair Muftah (2014-07-10)Es ist bekannt, dass Sport zu einer Modulation der Schmerzverarbeitung führt. Sportler weisen höhere Toleranzschwellen für Schmerz auf als Nichtsportler. Nach akuter sportlicher Aktivität tritt bei trainierten Athleten ... -
Longitudinalstudie zur Untersuchung der Wirksamkeit einer Ozontherapie im Zusammenhang mit der operativen Entfernung von Weisheitszähnen
Haddad, Kutaiba (2009-07-15)Medizinische Ozonanwendungen eröffnen neue therapeutische Aspekte. Über eine beschleunigte Wundheilung unter Ozongabe sowohl in Wasser als auch bei intraoraler, gasförmiger Applikation wurde mehrfach berichtet. Die gasförmige ... -
The Lords of Baakal: How an emblem glyph was shared in the Western Maya Lowlands
Markianos-Daniolos, Dimitrios (2022)The Baakal emblem glyph was one of the few emblems that were shared by different cities during the Classic Period. Originally appearing at Palenque, this emblem glyph would later be used by rulers at Tortuguero and Comalcalco. ... -
Lorentzkraftbildgebung: MR-basierte Darstellung Neuronaler Aktivität in Echtzeit
Bindl, Jakob (2019-02-12)In dieser Arbeit wurde eine neue Methode zur Darstellung neuronaler Aktivität in Echtzeit vorgestellt. Dabei wird die Lorentzkraft, die auf die elektrischen Ladungsträger aktiver Nervenzellen im Magnetfeld eines MR-Tomographen ... -
Los Señores del río y las lagunas: trabajo, epidemia y muerte entre los malebues del río Magdalena (Colombia): 1530-1611
Díaz Céspedes, Pedro Edwin (2024-03-28)Para el año de 1611, los Indios Navegantes o malebues del río Magdalena (norte de Colombia) en gran parte habían desaparecido. Según los resultados, el descenso de población había alcanzado el 97%; las poblaciones padecían ... -
Loss of Inhibitory CD33 Signaling Results in Increased Microglial Activation
Wißfeld, Jannis (2021-06-23)CD33 is expressed on immune cells of myeloid origin, such as macrophages and microglia. Upon activation, CD33 recruits and activates protein tyrosine phosphatases, which results in attenuation of the activatory signaling ... -
Loss of Profilin3 Impairs Spermiogenesis by Affecting Acrosome Biogenesis, Autophagy, Manchette Development and Mitochondrial Organization
Tariq, Naila (2022-12-02)
PFN4 is Required for Acrosome Biogenesis by Regulating Autophagy through PI3K/AKT/mTOR Pathway Loss of Profilin3 Impairs Spermiogenesis by Affecting Acrosome Biogenesis, Autophagy, Manchette Development and Mitochondrial Organization
Profilins (PFNs) are key regulatory proteins for the actin ... -
Loss of protamine 1 and actin-like 7b – Investigating genes relevant for male fertility
Merges, Gina Esther (2024-02-13)Sperm express a suite of genes specific to the testis. While they likely play essential roles in genes.
One of the key events during spermatogenesis is the replacement of histones by protamines. This leads to ... -
"Loud thunder, little rain" - participatory democracy in the European Union
Ho, Kwan Lok Alan (2021)Die Europäische Bürgerinitiative (EBI) lenkt die Beteiligung von Bürgerinnen und Bürgern von den Mitgliedsstaaten in die Europäische Union in einem beispiellosen Ausmaß. Die Erwartungen an sie und ihr Potenzial sind anfangs ... -
Low Dimensional Gauge Theories and Quantum Geometry
Ninad, Urmi (2020-10-14)This thesis explores the connection between supersymmetric gauge theories on curved spaces of dimensions two and three and geometries that arise in string theory. It does so by studying quantum field theoretic objects such ... -
Low Endotoxin Recovery: Wiederfindung und pyrogene Aktivität von Endotoxinen in pharmazeutischen Produkten
Negwer, Alexander (2021-08-06)Eine zuverlässige Überwachung bakterieller Kontaminationen ist entscheidend für die Herstellung und Sicherheit biopharmazeutischer Produkte. Die mikrobielle Sicherheit wird in der Regel (zusätzlich zu Sterilitätstests und ... -
Low mass hybrid pixel detectors for the high luminosity LHC upgrade
Gonella, Laura (2013-11-11)Reducing material in silicon trackers is of major importance for a good overall detector performance, and poses severe challenges to the design of the tracking system. To match the low mass constraints for trackers in High ... -
Low molecular weight polysialic acid prevents lipopolysaccharide-induced inflammatory dopaminergic neurodegeneration in humanized SIGLEC11 transgenic mice
Liao, Huan (2021-07-13)Parkinson’s disease is one of the most common neurodegenerative diseases in the elderly population, with a pathophysiology linked to neuroinflammation, complement activation and oxidative damage. Soluble polysialic acid ... -
Low-column density gas clumps in the inner and outer halo of the Milky Way
Ben Bekhti, Nadya (2009-03-30)More than 40 years ago the occurrence of several narrow absorption lines in QSO (quasi-stellar object) spectra was recognized for the first time (Bahcall 1966). Soon after their detection it became clear that the absorption ... -
Low-dimensional Representations for Diverse Collections of 3D Surface Meshes
Hahner, Sara Vera (2024-02-29)The surfaces of 3D shapes are discretized by surface meshes that represent them in a processable way. This enables simulations of deforming components in CAE, animations for movies, or representations of human organs to ... -
Low-energy scattering on the lattice
Bour Bour, Shahin (2014-06-24)In this thesis we present precision benchmark calculations for two-component fermions in the unitarity limit using an ab initio method, namely Hamiltonian lattice formalism. We calculate the ground state energy for unpolarized ...