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Moduli spaces of branched coverings of the plane
(2020-07-03)In this thesis I build a strong connection between Hurwitz spaces of branched coverings of the complex plane, and moduli spaces M_{g,n} of Riemann surfaces of genus g ≥ 0 with n ≥ 1 boundary components.
I refine a ... -
Moduli spaces of K3 surfaces and cubic fourfolds
(2019-11-14)This thesis is concerned with the Hodge-theoretic relation between polarized K3 surfaces of degree d and special cubic fourfolds of discriminant d, as introduced by Hassett.
For half of the d, ... -
Die modulierende Wirkung von Aptameren auf die Eigenschaften und Funktionen von Thrombin
(2012-12-10)Thrombin ist ein multifunktionelles Enzym, dem eine zentrale Rolle in der Aktivierung und Regulation der Gerinnungsantwort zukommt. Dazu interagiert es mit verschiedenen makromolekularen Substraten. Auf molekularer Ebene ... -
Modulierung der Guaninnukleotid Austauschfaktoren Tiam1 und Vav1 durch RNA-Aptamere
(2011-11-29)Die vorliegende Arbeit beschäftigt sich mit der in vitro Selektion von spezifisch bindenden RNA-Aptameren gegen die Dbl-homologe Domäne der Rho-GEFs Tiam1 und Vav1. Einhergehend mit der spezifischen Bindung sollten die ... -
Molar dentition of the docodontan Haldanodon (Mammaliaformes) as functional analog to tribosphenic teeth
(2019-06-18)All extant mammals save the monotremes descend from an ancestor with tribosphenic tooth morphology, characterized by a distally situated crushing basin (talonid basin) on the lower and an interlocking cusp (protocone) on ... -
Molecular absorption in the cores of AGN: On the unified model
(2008)One of the fundamental concepts in the unified scheme of AGN is that both Seyfert 1 and Seyfert 2 galaxies harbour supermassive black holes that act as nuclear engines, but in Seyfert 2 galaxies the nucleus is blocked ...
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Molecular Analysis of Genes Involved in the Biosynthesis and Regulation of Hormaomycin, an Exceptionally Complex Bacterial Signaling Metabolite
(2013-10-21)Hormaomycin (HRM) is a nonribosomal peptide antibiotic isolated from Streptomyces griseoflavus W-384. It contains several unprecedented nonproteinogenic building blocks bearing chlorine, nitro or cyclopropyl ... -
Molecular Analysis of the Chlamydial Anomaly: Role of the cytoskeleton protein MreB, the serine hydroxymethyl transferase GlyA and the penicillin binding proteins from Chlamydophila pneumoniae
(2012-09-27)Chlamydiae are Gram-negative, obligate intracellular pathogens. Because of the isotonic intracellular niche of the host, a functional cell wall is dispensable in these endobacteria. Surprisingly, a nearly complete pathway ... -
Molecular analysis of the plastid-targeted gene and protein (CpPTP-1) associated with desiccation tolerance in the resurrection plant Craterostigma plantagineum
(2021-01-28)Water scarcity causes drought stress and enormous losses in agricultural production, and consequently this leads to a worldwide food crisis. Craterostigma plantagineumis one of the best studied resurrection plants ... -
Molecular and biochemical studies of the Craterostigma plantagineum cell wall during dehydration and rehydration
(2020-02-17)Craterostigma plantagineum belongs to the desiccation tolerant angiosperm plants. Upon dehydration leaves fold and the cells shrink which is reversed during rehydration. To understand this process changes in cell ... -
Molecular and functional characterization of inflammation-induced cell state transitions in malignant-transformed melanocytes
(2019-10-08)Cellular phenotype plasticity is a hallmark of embryonic development in order to achieve cell type specification from precursor populations. The molecular mechanisms orchestrating phenotypic plasticity are of interest ... -
Molecular and physiological characterization of transgenic Arabidopsis plants expressing different aldehyde dehydrogenase (ALDH) genes
(2005)Various reactive molecules such as aldehydes and their intermediates accumulate in plants exposed to environmental stress conditions. These molecules are highly toxic and can cause peroxidation of cellular lipids, protein ... -
Molecular Approach toward Gases Absorption by Ionic Liquids
(2017-01-24)This thesis reports the theoretical studies of gas absorption in complex systems. These systems, namely ionic liquids, are considered to be promising candidates to substitute conventional gas capture systems which violate ... -
Molecular characterization of porcine genes encoding complement components of the terminal lytic pathway and their association with hemolytic complement activity
(2009-06-02)Activation of the complement system from three different pathways (classical, alternative and lectin pathway) results in the generation of the C3-convertase enzyme, which plays a key role in formation of the membrane attack ... -
Molecular Characterization of Quality Control Factors at the Protein Entry Gate of Mitochondria
(2024-04-04)(noch nicht zugänglich / not yet accessible) -
Molecular characterization of the maize (Zea mays L.) AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA) gene family
(2014-10-17)The phytohormone auxin is an important molecular component in plant signal transduction. As an endogenous signaling molecule, auxin controls many aspects of plant development. Members of the AUXIN/INDOLE-3-ACETIC ACID ... -
Molecular Complexity Effects and Fingerprint-Based Similarity Search Strategies
(2009-11-13)Molecular fingerprints are bit string representations of molecular structure and properties. They are among the most popular descriptors and tools in molecular similarity searching because of their conceptual simplicity ... -
Molecular determinants of prostate cancer aggressiveness: an analysis of the interconnection between biomarkers,disease drivers and resistance mechanisms towardsnovel diagnostic, theranostic and therapeutic approaches
(2023-06-21)The diagnosis of prostate cancer (PCa) is still mainly based on morphological criteria but is supported by biomarker analysis, which is currently mainly performed on an immunohistochemical basis. Newly developed techniques ... -
Molecular diversity in early stage high-mass protostars
(2022-11-30)During star formation, the molecular gas undergoes significant chemical evolution with the emergence of dense cores harboring hot cores and hot corinos, rich in complex organic molecules (COMs). The formation pathways, ... -
Molecular Dynamics Simulations of the Bacterial Outer Membrane Channels TolC and OprM & dxTuber, a Biomolecular Cavity Detection Tool based on Protein and Solvent Dynamics
(2013-09-12)The multidrug resistance of bacteria is a serious phenomenon in current medical treatment. Beginning with the introduction of antibiotics more and more bacterial strains achieved resistance against these chemical compounds ...
