Browsing by Subject "RabGEF1"
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Chemical modulation of guanine nucleotide exchange factor activity: A small molecule inhibitor for the Rabex-5 mediated Rab5 activation
Wosnitza, Christine Irene (2013-09-02)The small GTPase Rab5 is a key regulator in the early endocytic pathway. The activity of Rab5 is controlled by numerous guanine nucleotide exchange factors (GEFs), which catalyse the exchange of GDP for GTP. However, the ...