E-Dissertationen: Browsing E-Dissertationen by Title
Now showing items 1749-1768 of 4070
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Identifying intracellular cisplatin interaction partners and assessing their contribution to cisplatin resistance
Kullmann, Maximilian (2016-10-24)Intracellular binding of cisplatin to non-DNA partners, such as proteins, has received increasing attention as an additional mode of action as well as a mechanism of resistance. In this project three cisplatin-interacting ... -
Image-Based Approaches to Hair Modeling
Lay Herrera, Tomás (2013-06-06)Hair is a relevant characteristic of virtual characters, therefore the modeling of plausible facial hair and hairstyles is an essential step in the generation of computer generated (CG) avatars. However, the inherent ... -
Imaging a life span: In vivo Magnetic Resonance Imaging of Development and Ageing in Rat and Mouse Brain
Hammelrath, Nicola Luam Kidane (2016-01-28)Rats and mice are the most abundantly used animal models in translational research. They are employed in the service of clinical research in the sense of establishing methods, testing therapeutic strategies and pharmacological ... -
Imaging Meningiomas: The Road to the First Medical Application of the Novel Magnetic Resonance Rheology
Theilenberg, Sebastian (2017-04-25)In this thesis the first application of Magnetic Resonance Rheology (MRR) to patients with known brain lesions was presented.
MRR is a novel approach to image the mechanical properties of brain tissue in vivo. It ... -
Imaging Outside The Box: Enhancing the Performance and Applicability of Time-of-Flight Sensors through Computational Sensing
Callenberg, Clara (2022-12-12)Time-of-Flight (ToF) imaging, which allows to measure the time that light has taken to travel from a light source to a camera, is an increasingly relevant sensing modality. ToF imagers are used, for example, in smartphones, ... -
Immune modifying effect of drug free PLGA nanoparticles on the course of experimental autoimmune neuritis (EAN)
Elahi, Ehsan (2024-03-15)Experimental autoimmune neuritis (EAN) animal model mimics the human Guillain-Barre syndrome (GBS), an autoimmune disease of demyelination and inflammation of peripheral nerves. Despite advancement in clinical management ... -
Immune modulation by experimental filarial infection and its impact on E. coli-induced sepsis
Gondorf, Fabian (2015-11-12)Helminths cause so-called neglected tropical diseases in tropical and sub-tropical regions and are prevalent in almost one third of mankind. Thus, co-infections of helminths with other pathogens are common. However, the ... -
Immune regulation in Plasmodium berghei ANKA infected mice either lacking type I interferon signalling or mimicking malaria tolerance
Korir, Patricia Jebett (2017-03-16)Malaria is a disease caused by Plasmodium parasites and transmitted by female Anopheles mosquitoes. Children under the age of five, pregnant women and none-immune individuals are at risk of developing ... -
Immune Regulation in Human Filariasis
Arndts, Kathrin (2013-03-14)Vector transmitted diseases such as the tropical helminth infections onchocerciasis and lymphatic filariasis (LF) affect more than 150 million people worldwide and are both considered major public health concerns. In order ... -
The immunomodulatory capacity of helminths on inflammation: Impact of eosinophils on E. coli-induced sepsis and genome-wide transcriptome profiling of human monocytes stimulated with helminth extract and LPS implicate immune functions and diseases
Bürfent, Benedikt Christian (2017-10-19)Human filarial nematode infections cause lymphatic filariasis and onchocerciasis in more than 150 million people worldwide. An infection can result in debilitating clinical manifestations like visual impairment or lymphedema ... -
Immunregulation durch alternative Antigenpräsentation am Beispiel der HCV- und HIV-Infektion
Schulte, Daniela (2011-01-28)Das nicht-klassische MHC-I Molekül HLA-E spielt eine bedeutende Rolle bei der Regulation der NK-Zell-vermittelten Zytotoxizität und der zytotoxischen CD8(+) T-Zellantwort. Im Gegensatz zu klassischen MHC-I Molekülen ist ... -
Immuntoxinproduktion in Pflanzen: Eine innovative Methode zur Herstellung neuartiger Therapeutika gegen das Hodgkin Lymphom
Becker, Stefanie (2006)Immuntoxine bergen ein großes Potenzial in der Therapie des Hodgkin Lymphoms. Als Zielantigene können hier CD25 und CD30 gewählt werden, welche beide auf den entarteten Reed-Sternberg-Zellen überexprimiert werden. Die ... -
Impact and Range Extension of Invasive Foraminifera in the NW Mediterranean Sea: Implications for Diversity and Ecosystem Functioning
Mouanga, Gloria Hortense (2018-01-18)Climate warming and the poleward widening of the tropical belt have induced range shifts in a variety of marine and terrestrial organisms. Among the key taxa that are rapidly expanding their latitudinal range are larger ... -
The impact and underlying molecular mechanisms of cell adhesion molecules integrins and syndecans in the cisplatin chemoresistance of melanoma cells
Rossi Piva, Maria Bethania (2019-12-06)Cancer is a complex, but also devastating disease, which today, more than ever, is present in our lives and society. Practically every person has a close relative or friend, or has been themselves affected by this disease. ... -
Impact assessment of global change on wetland-catchment interactions in a tropical East African catchment
Näschen, Kristian (2020-02-27)Water is the key to sustainable development, especially in sub-Saharan Africa (SSA), where a large part of the population lives on subsistence farming. Reliable knowledge of available water resources therefore is an ... -
Impact Assessment of Land-Use Change and Agricultural Treatments on Greenhouse Gas Emissions from Wetlands of Uganda and Tanzania
Wagner, Katrin Xin Xin (2020-02-04)Wetlands play an important role in global climate regulation as they represent a great global carbon sink. Moreover, wetlands provide optimal conditions for food production and support the livelihoods of many people in ... -
Impact of UGT1A polymorphisms on inflammation and fibrogenesis in a humanized transgenic mouse model
Landerer, Steffen (2020-07-07)Fibrogenesis represents a highly dynamic scarring response of the liver resulting from different causes of hepatic injury. A key process capable of activating a broad array of profibrogenic pathways is oxidative stress. ... -
The impact of artificial lights and anthropogenic noise on Loggerheads (Caretta caretta) and Green Turtles (Chelonia mydas), assessed at index nesting beaches in Turkey and Mexico
Magyar, Thomas (2009-06-02)Coastal development is considered to be a significant hazard that endangers sea turtles by destroying nesting space. If uncontrolled, it will result in decline and local extinction, or will prevent recovery of these ... -
The impact of binary interaction on the main-sequence morphology of young star clusters
Wang, Chen (2022-03-04)Star clusters play a vital role in our understanding of stellar physics and evolution, because they are believed to contain stars born at the same time, with the same initial conditions. Therefore, the distribution of the ... -
The Impact of CD44 and Osteopontin on Hematopoiesis
Brandes, Maria (2021-10-25)Hematopoiesis is the process, which enables the replenishment of blood cellular components in mammals throughout their lifespan. Hematopoietic stem cells (HSC), which reside within the bone marrow (BM), are the primary ...