E-Dissertationen: Browsing E-Dissertationen by Title
Now showing items 2069-2088 of 4067
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Liposomale Zytostatika zur Untersuchung und Überwindung von Chemoresistenzen in Ovarialkarzinom-Zellen
Borrmann, Michaela Lilian (2016-07-26)Der klinische Einsatz von Zytostatika, wie Cisplatin und Doxorubicin wird oftmals durch Resistenzbildung der Tumore gegen diese Wirkstoffe massiv eingeschränkt. Resistenzmechanismen können u.a. in einem verminderten ... -
The Liprin-α protein family: common and diverging properties
Zürner, Magdalena (2010-12-21)The Liprin-α family of scaffolding proteins is highly evolutionary conserved. While one homologue is present in invertebrates, it has diversified into four isoforms in mammals. In invertebrates, Liprin-α plays a crucial ... -
„Liver-primed T cells“ - eine neue Population von Gedächtnis T Zellen
Böttcher, Jan Philipp (2013-07-25)Die lokalen antigen-präsentierenden Zellen (APC) der Leber sind konstant zirkulierenden Antigenen mit unbekannter Herkunft ausgesetzt. Solche löslichen Antigene werden bevorzugt von sinusoidalen Endothelzellen der Leber ... -
Livestock Water Productivity (LWP) improvement in the mixed croplivestock system of Ethiopian Highlands, Amhara Region: a gendered sustainable livelihood approach to target LWP interventions for rural poverty reduction
Demissie Tegegne, Sewmehon (2012-01-12)Water is vital for live as such including a wide range of livelihood activities including domestic and productive needs. Access to adequate water supply would significantly contribute to poverty alleviation, whereas lack ... -
LM-PAFOG - a new three-dimensional fog forecast model with parametrised microphysics
Masbou, Matthieu (2008)The presence of fog and low clouds in the lower atmosphere can have a critical impact on both airborne and ground transports and is often connected with serious accidents. An improvement of fog forecasts in terms of ...
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Local L(2)-Cohomology of Shimura Varieties
Meusers, Volker (2008)We give a new proof of Zuckers Conjecture relating the intersection cohomology of a locally symmetric variety to its L2-cohomology. This is achieved using techniques developed by Jens Franke in his proof of the Borel conjecture. -
Local Gauge Coupling Running in Supersymmetric Gauge Theories on Orbifolds
Hillenbach, Mark (2007)By extending Feynman's path integral calculus to fields which respect orbifold boundary conditions we provide a straightforward and convenient framework for loop calculations on orbifolds. We take advantage of this general ... -
Local Smoothing and Well-Posedness Results for KP-II Type Equations
Kalantarova, Habiba (2015-04-22)We study two equations of KP-II type: the Kadomtsev-Petviashvili II equation and its cubical generalization (gKP-II)$_{3}$.
In Chapter 3, we discuss the qualitative properties of the Kadomtsev-Petviashvili II equation ... -
Localization and functional role of RIM3γ and RIM4γ, the small members of the RIM protein family
Álvarez-Barón Fuentes, Elena (2010-05-19)RIMs are Active Zone enriched multidomain proteins. In vertebrates, the RIM family is composed of 7 proteins (RIM1α, 2α, 1β, 2β, 2γ, 3γ and 4γ) encoded by four different genes (RIM1-4). The large members of the RIM protein ... -
Localization of Paramagnetic Metal Ions in Biomolecules ny means of Electron Paramagnetic Resonance
Abdullin, Dinar (2017-03-23)Localization of metal ion binding sites in biomolecules is an important objective in structural biology. Experimental methods that are commonly used to determine the location of metal ions, such as X-ray crystallography ... -
Locus coeruleus modulates locomotor activity via the medial septum and the diagonal band of Broca
Ludwig, Felix (2020-10-02)The locus coeruleus (LC) is positioned in the brainstem and one of the main sources of norepinephrine in the brain. With its projections throughout the whole brain, the LC plays an important role in regulating the general ... -
Lokale Gitterumgebung von Indium in GaN, AlN und InN
Penner, Jakob (2007)Die Produktion und die Anwendung der Gruppe III Nitridhalbleiter, besonders vertreten durch das Material GaN, haben in den letzten Jahren ein enormes Wachstum genossen. Die Synthese ternärer Legierungen wie GaxLokale und regionale Gefahren- und Risikoanalyse gravitativer Massenbewegungen an der Schwäbischen Alb
Bell, Rainer (2007)In den deutschen Mittelgebirgen werden die Gefahren und Risiken durch gravitative Massenbewegungen häufig unterschätzt. Die meisten Autoren gehen davon aus, dass die größten gravitativen Massenbewegungen während des ...Lokaler Gentransfer und Zellpositionierung mittels magnetischer Nanopartikel für die Generierung optogenetischer und biologischer Herzschrittmacher
Kilgus, Carsten (2014-10-17)Herzrhythmusstörungen sind Unregelmäßigkeiten der Herzfrequenz, welche für die erkrankten Patienten eine vitale Gefährdung darstellen und sogar tödlich verlaufen können. Ursachen liegen häufig in Störungen des Erregungsbildungs- ...Lokalisation des mechanisch regulierten Cochaperons BAG3 und ausgewählter Bindepartner in Muskelzellen
Friedrich, Julia (2023-10-24)(noch nicht zugänglich / not yet accessible)Long bone histology of basalmost and derived Sauropodomorpha: the convergence of fibrolamellar bone and the evolution of giantism and nanism
Stein, Koen Hendrik Willy (2012-01-11)This study reports on long bone histology and growth in sauropodomorph dinosaurs. Derived members of Sauropodomorpha, the sauropods, were the largest terrestrial animals our planet has ever seen. New methods have recently ...Long-term timing of pulsars in globular clusters
Ridolfi, Alessandro (2017-12-20)Pulsars are fast rotating, magnetized neutron stars that result from the supernova explosion of massive stars. Thanks to their coherent radiation, emitted in the form of collimated beams from the two magnetic poles, pulsars ...Long-timescale atomistic simulations
Bulin, Johannes (2021-03-31)The simulation and analysis of particle systems dynamics is an important subfield of computational materials science. It allows the investigation of many properties of interest, such as reaction mechanisms, diffusion rates, ...Lorentzkraftbildgebung: MR-basierte Darstellung Neuronaler Aktivität in Echtzeit
Bindl, Jakob (2019-02-12)In dieser Arbeit wurde eine neue Methode zur Darstellung neuronaler Aktivität in Echtzeit vorgestellt. Dabei wird die Lorentzkraft, die auf die elektrischen Ladungsträger aktiver Nervenzellen im Magnetfeld eines MR-Tomographen ...Loss of Inhibitory CD33 Signaling Results in Increased Microglial Activation
Wißfeld, Jannis (2021-06-23)CD33 is expressed on immune cells of myeloid origin, such as macrophages and microglia. Upon activation, CD33 recruits and activates protein tyrosine phosphatases, which results in attenuation of the activatory signaling ...