E-Dissertationen: Suche
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Crossregulation of Insulin signalling and innate immunity
(2010-08-10)
Insulin signalling (IlS) is a major signalling cascade, which is conserved from worm to human. Beside the regulation of blood sugar levels, different other processes like organismal growth, body size, ageing or autophagy ...
Biochemical and functional analysis of innexin2-containing gap junction channels during organogenesis in Drosophila
(2009-05-13)
Gap junctions channels serve as mediators for direct cell-to cell communication between cells of different tissues and organs by the exchange of small metabolites and signalling molecules. They are formed by analogous ...
Die Funktion des Drosophila NHL-Domänen Proteins Wech und seiner Interaktionspartner in der Integrin-vermittelten Zelladhäsion
(2008)
Die Verbindung der Muskeln mit dem Exoskelett wird in Drosophila durch die Tendonzelle vermittelt. Die dabei entstehende Struktur bezeichnet man als epidermale Muskelanhaftungsstelle. Für die endgültige und dauerhafte ...
The Control of Food Intake and Bitter Taste Information Processing in the Drosophila Larval Brain
(2016-12-22)
The regulation of feeding behavior by central neural circuits is crucial for every organism to survive. Hierarchical organized motor systems are responsible for the execution of appropriate feeding movements and can be ...
Funktionelle Charakterisierung der Chaperon-assoziierten Ubiquitinligase CHIP in Drosophila melanogaster
(2016)
In der vorliegenden Arbeit konnte die Chaperon-assoziierte Ubiquitinligase CHIP als zentrales Bindeglied zwischen Proteinhomöostase („Proteostase“) und Alterung identifiziert werden. Neben seiner Rolle als Proteinqualitä ......
Molecular mechanisms of extracellular matrix dynamics at barrier tissues and control of molting in Drosophila
(2017-04-19)
The insect epidermal cuticle acts as the exoskeleton and has crucial barrier functions, protecting against wounding, desiccation, invading pathogens and other environmental dangers. During the life of insects, the epidermal ......
Actin Regulatory Proteins in Dendritic Arborisation Neurons of Drosophila
(2019-10-23)
Dendrites are highly branched extensions of nerve cells, along which signals are received and propagated to the cell body. The correct morphology of dendrites is essential for the function of the nervous system. The ...
Sleep and navigation in Drosophila
(2023-12-20)
Sleep plays an essential role in life and is critical for the optimal functioning of the brain, for example in learning and memory. Drosophila displays many of the signatures of sleep observed in mammals or humans, including ...