E-Dissertationen: Search
Now showing items 1-2 of 2
Benzimidazol-Analoga als Modulatoren von ABC-Transportern
(2011-10-17)
Humane ABC-Transporter (ATP-Binding-Casette) wie P-Glykoprotein (P-gp), die Multidrug Resistance associated Proteine (MRPs) oder Breast Cancer Resistance Protein (BCRP) stellen für die Arzneimitteltherapie einen sehr ...
Purines and 9-deazapurines as Modulators of Multidrug Resistance-associated Protein 1 (MRP1/ABCC1)-mediated Transport
(2017-11-14)
Expression of ABC-transport proteins is a major obstacle in cancer chemotherapy. Especially MRP1, P-gp and BCRP are expressed in different malignancies like lung cancer, colon carcinomas, leukemias, bladder cancer, myeloma, ...