Anzeige der Dokumente 1-2 von 2
The contribution of the sodium channel subunit Na<sub>V</sub>1.6 to neuronal excitability
The focus of this work was to elucidate the contribution of a single Na<sup>+</sup> channel a-subunit, namely Na<sub>V</sub>1.6, to the discharge properties of CA1 pyramidal neurons. In the first part of this work, we show ...
Hippocampal cellular and network properties in a mouse model of metachromatic leukodystrophy
The human disease of metachromatic leukodystrophy (MLD) is caused by a single or multiple allelic mutations within the gene locus of arylsulfatase A (ASA). This protein is a lysosomal enzyme catalyzing the degradation of ...