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The implication of microglial sialic acid-binding immunoglobulin-like lectin-E (Siglec-E) in neuroinflammation
Microglia are the resident immune cells of the central nervous system (CNS). They display a whole set of recognition receptors on their cell surface to sense intact or lesioned cells in the CNS. A subfamily of these receptors ...
The role of endocannabinoid system in neuron-glial communication in the ageing and diseased brain
The endocannabinoid system has been implicated in the regulation of glial activity and progression of brain ageing. Mice constitutively or specifically lacking the cannabinoid receptor 1 (CB1) on neurons or GABAergic neurons ...
The role of the endocannabinoid system in stress-related disorders and neuroimmune communication
In the last decades, increasing evidence suggests that inflammatory processes play an important role in the development of psychiatric disorders, such as anxiety and depression. Psychosocial stress – one of the main ...