E-Dissertationen: Suche
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RIMs and RIM interacting proteins: localization and function under physiological and pathophysiological conditions
(2011-02-25)
Neurons transmit signals to their target cells at specialized contact sites called synapses. At chemical synapses the signal propagation is mediated by the fusion of neurotransmitter filled synaptic vesicles with the ...
Copy number variations of the mitochondrial DNA as potential cause of mitochondrial diseases
(2010-12-30)
Aim: The aim of this thesis was the analysis of copy number variations of the mitochondrial DNA (mtDNA) in several tissues and cell types with regard to different mitochondrial associated disorders.
Background: The ...
Background: The ...
The contribution of the sodium channel subunit NaV1.6 to neuronal excitability
(2010-04-13)
The focus of this work was to elucidate the contribution of a single Na+ channel a-subunit, namely NaV1.6, to the discharge properties of CA1 pyramidal neurons. In the first part of this work, we show ...