E-Dissertationen: Search
Now showing items 11-20 of 210
Numerical Methods in Shape Spaces and Optimal Branching Patterns
(2017-04-25)
The contribution of this thesis is twofold. The main part deals with numerical methods in the context of shape space analysis, where the shape space at hand is considered as a Riemannian manifold. In detail, we apply and ......
Quantum Phase Transitions in Multi-Impurity and Lattice Kondo Systems
(2017-04-25)
The main purpose of this dissertation is to provide a detailed development of a self-consistent perturbative renormalization group (RG) method to investigate the quantum phases and quantum phase transitions of multi-impurity ...
Prevalence of resistance-nodulation-cell division-type efflux pumps and their contribution to antimicrobial resistance in Acinetobacter baumannii
(2017-03-29)
Over the past three decades A. baumannii has evolved into a clinically important nosocomial pathogen causing epidemic outbreaks worldwide. Due to its intrinsic antimicrobial resistance and its ability to easily acquire new ......
Geometrical Methods for the Analysis of Simulation Bundles
(2017-03-29)
Efficiently analyzing large amounts of high dimensional data derived from the simulation of industrial products is a challenge that is confronted in this thesis. For this purpose, simulations are considered as abstract ...
Massive stars on the main sequence
(2017-03-10)
Massive stars have a strong influence on their environment by chemical enrichment of the surrounding interstellar medium due to strong stellar winds. The influence of mass loss and rotation on the main-sequence evolution ...
Cosmological Investigations On Large And Small Scales
(2017-03-03)
The standard model of cosmology, founded on Einstein’s theory of gravity and on the Cosmological Principle (CP), has been understood as being successful in providing explanations for many observations so far. However, it ...
The role of sphingosine-1-phosphate lyase (SPL) in the brain: Studies in brain-targeted SPL-deficient mice
(2017-05-15)
The bioactive lipid sphingosine 1-phosphate (S1P) is a degradation product of sphingolipids that are particularly abundant in neurons. It was shown previously that neuronal S1P accumulation is toxic leading to ER-stress ...
Untersuchungen zur Chemie transienter Phosphanoxylverbindungen
(2017-12-20)
Im Zuge dieser Arbeit wurden Phosphane und Phosphankomplexe mit einem sauerstoffgebundenen TEMPO-Substituenten synthetisiert und im Hinblick auf die ambivalente homolytische Bindungsspaltung der P–O- und O–N-Bindungen ...
Identification, optimization and characterization of pharmacological tools for the cannabinoidactivated orphan G protein-coupled receptor GPR18 and related receptors
(2017-12-21)
Cannabinoid receptors comprise two classical subtypes, CB1 and CB2, which belong to the large family of G protein-coupled receptors (GPCRs). They are the major targets of cannabinoids such as ......
Analyse der Funktion von Dynamin2 in der Integrin-vermittelten Adhäsion humaner T-Lymphozyten
(2017-11-08)
Das Immunsystem ist ein dezentralisiertes Organ, dessen zelluläre Bestandteile dazu in der Lage sein müssen, ihre Aufenthaltsorte innerhalb des Körpers rasch zu verändern, um effektive Immunantworten zu gewährleisten. So ...