E-Dissertationen: Search
Now showing items 3451-3460 of 4070
Pharmacokinetic-pharmacodynamic modeling of antibacterial agents in tissues and body fluids
(2020-11-25)
The aim of this thesis was to assess the pharmacokinetic / pharmacodynamics (PK/PD) of anti-bacterial agents in tissues and body fluids through non-linear mixed effects (NLME) modeling.
In the first project, a ...
In the first project, a ...
Approximation Algorithms for the Traveling Salesman Problem
(2021-05-11)
The traveling salesman problem (TSP) is probably one of the best-studied problems in discrete optimization. Given a complete weighted graph with n vertices, the task is to find a tour of minimal length that visits every ...
On the imidazole-2-thione-based route to tricyclic 1,4-diphosphinines: synthesis, structures and reactions
(2018-02-15)
The PhD Thesis “On the imidazole-2-thione-based route to tricyclic 1,4-diphosphinines: synthesis, structures and reactions” describes the synthetic concept to and first studies on the chemistry of novel tricyclic ......
Synthesis, Characterization and Reactivity of Ylidyne and μ-Ylido Complexes Supported by Scorpionato Ligands
(2018-02-21)
The chemistry of compounds featuring triple bonds of the heavier Group-14 elements Si–Pb with transition metals is a very challenging research area, which combines modern molecular main-group element with transition-metal ......
Untersuchung der präferentiellen und alternativen Signalwegsaktivierung muskarinischer M2- und M4-Rezeptoren mithilfe von molekularen Testsonden
(2018-02-16)
Die muskarinischen Acetylcholinrezeptoren gehören zur Superfamilie der 7-Transmembranrezeptoren. Die in der vorliegenden Arbeit betrachteten M2- und M4-Rezeptoren weisen eine präferentielle Kopplung ...
The impact of tides and mass transfer on the evolution of metal-poor massive binary stars
(2018-05-24)
Stars more massive than 10Msun , although few in number compared to objects like our sun, play a very large role in the evolution of the universe. Through strong winds and supernovae they enrich the interstellar medium ...
Quantum Chemical Calculation of Electron Ionization Mass Spectra
(2018-03-06)
This thesis reports the computation of electron ionization (EI) mass spectra using a method that combines statistical theory and molecular dynamics. Due to the complexity of the unimolecular reaction space, not all competing ......
Evolution of carbon-enhanced metal-poor stars originating from mass transfer in stellar binaries
(2018-03-26)
As the hydrogen and helium created shortly after the Big Bang is gradually processed into heavier elements by successive generations of stars, the overall metal content of the Universe increases. Metal-poor stars which, ...
Supra-molecular structures at the cytoplasmic periphery of the plasma membrane
(2018-02-15)
The self-assembly of biomolecules into supra-molecular structures is an important principle underlying cellular organization. These structures define spatial environments for diverse biological processes. In particular, ...
Spatio-Temporal Estimation and Validation of Remotely Sensed Vegetation and Hydrological Fluxes in the Rur Catchment, Germany
(2018-03-07)
Operational availability of spatio-temporal vegetation and hydrological estimates are becoming increasingly attractive for hydrologic studies from local through regional and global scales, especially in remote areas and ...