E-Dissertationen: Suche
Anzeige der Dokumente 41-50 von 218
Structural conformational analysis of molecular dynamics of a P-glycoprotein homology model and generated intermediate structures
(2019-10-02)
The major reason for failure of chemotherapy in cancer is multidrug resistance. A mechanism by which human cancers develop multi-drug resistance is over expression of certain ATP-binding cassette (ABC) transporters. ...
Characterization of the functional role of the Cystein-rich with EGF-like domains (Creld) protein in mitochondrial quality control in Drosophila melanogaster
(2019-08-01)
Cystein-rich with EGF-like domains (Creld) proteins belong to a protein family conserved between species. The mammalian genome contains two Creld genes. Unraveling the function of mammalian Creld proteins has been tried ...
Renormalisation in discrete elasticity
(2019-10-10)
This thesis deals with the statistical mechanics of lattice models. It has two main contributions. On the one hand we implement a general framework for a rigorous renormalisation group approach to gradient models. This ...
Synthetic evolution of azobenzene and arylazopyrazole photoswitches and translation into photoresponsive DNA nanosystems
(2019-10-23)
Light as an external stimulus provides a powerful and versatile tool to control chemical reactions and biological systems. Light is easily available and permits a high spatial and temporal control while minimizing systemic ......
Complex organic chemistry in high-mass star forming regions
(2019-10-22)
The quest for interstellar complex organic molecules (COMs) lies at the heart of astrochemistry. One basic motivation is to figure out how the rich inventory of COMs found in meteorites and comets is connected to interstellar ...
Effects of intracranial stimulation and the involvement of the human parahippocampal cortex in perception
(2019-10-04)
How the human brain translates photons hitting the retina into conscious perception remains an open question. Throughout the medial temporal lobe (MTL), there are neurons (called concept cells) that change their firing ...
Alternative splicing as a regulatory mechanism of the NLRP3 inflammasome
(2019-10-09)
The innate immune system relies on germ-line encoded pattern recognition receptors and is critically involved in the early sensing of pathogens and disturbances of cell homeostasis. Upon activation by pathogenic or sterile ...
Open Topological Field Theories and 2-Segal Objects
(2019-10-17)
In this thesis we analyze 2-dimensional open topological field theories in both 1-categorical and ∞-categorical contexts. Making use of the formalism, introduced by Dyckerhoff and Kapranov, of graphs structured over a ......
Untersuchungen zu Biotensid produzierenden epiphyllen Pseudomonaden
(2019-10-16)
Die Phyllosphäre umfasst den gesamten Lebensraum auf Blattoberflächen und bildet eine der größten ökologischen Nischen für mikrobielles Leben auf organischen Oberflächen. Zu den häufigsten Bewohnern der Phyllosphäre gehören ......
Small embeddings, forcing with side conditions, and large cardinal characterizations
(2019-09-26)
In this thesis, we provide new characterizations for several well-studied large cardinal notions. These characterizations will be of two types. Motivated by seminal work of Magidor, the first type characterizes large ...