E-Dissertationen: Search
Now showing items 51-60 of 218
Cutin, wax and stomatal mutants of Arabidopsis thaliana: chemical and physiological analysis of the leaf barrier properties
(2019-10-08)
Stomatal pores and the cuticular membrane are the two major key elements to regulate the gas exchange and water balance of plants. The hydrophobic cuticle covers all aerial parts of plants in their primary developmental ......
The plesiosaur: remarkable morphology, histology, and physiology
(2019-07-04)
In this dissertation, contributions to understanding the morphology, histology, and physiology of plesiosaurs, a major group of marine reptiles from the Age of Dinosaurs, are presented. By using comparative methods and new ......
Anordnung und Test der Detektor-Submodul-Komponenten für die Vorwärts-Endkappe des PANDA-EMC
(2019-07-16)
Ein großer Schritt zum besseren Verständnis des Standardmodells der Teilchenphysik ist die Beschreibung der Quantenchromodynamik (QCD) im Bereich der nicht störungstheoretisch berechenbaren Energieüberträge. In diesem ......
Matching and test of the forward-endcap detector-submodule-components for the PANDA-EMC
A large step towards a better understanding of the standard model of particle physics is the description of ......
Matching and test of the forward-endcap detector-submodule-components for the PANDA-EMC
A large step towards a better understanding of the standard model of particle physics is the description of ......
Expression and Function of ErbB4 Splice Variants in the Central Nervous System
(2019-07-18)
Neuregulins and their cognate neuronal receptor tyrosine kinase ErbB4 (avian erythroblastosis virus oncogene B4) are genetically linked with an increased risk for schizophrenia. NRG/ErbB4 signaling regulates neurodevelopment, ......
Neureguline und ihr neuronaler Tyrosinkinaserezeptor ErbB4 (avian erythroblastosis virus oncogene B4) sind genetisch mit einem erhöhtem Risiko für Schizophrenie assoziiert. NRG/ErbB4 Signalübertragung reguliert unter anderem ......
Neureguline und ihr neuronaler Tyrosinkinaserezeptor ErbB4 (avian erythroblastosis virus oncogene B4) sind genetisch mit einem erhöhtem Risiko für Schizophrenie assoziiert. NRG/ErbB4 Signalübertragung reguliert unter anderem ......
Pharmacometric approaches for linking pharmacokinetic and pharmacodynamic models of sunitinib and pazopanib with clinical outcome
(2019-07-22)
Aim of this thesis was to build a modeling framework for patients with metastatic renal cell carcinoma (mRCC) treated with two common first-line therapies, sunitinib and pazopanib. Therefore, as part of the European-wide ...
Strategies for the intelligent integration of genetic variance information in multiscale models of neurodegenerative diseases
(2019-07-18)
A more complete understanding of the genetic architecture of complex traits and diseases can maximize the utility of human genetics in disease screening, diagnosis, prognosis, and therapy. Undoubtedly, the identification ...
FR900359, an inhibitor of guanine nucleotide dissociation, effectively blunts signaling of GTPase-deficient Gq: mechanism of action and relevance for treating Gq-driven cancers
(2019-08-01)
Uveal melanoma (UM), the most common cancer of the adult eye, is known to have poor prognosis. Over 50% of patients are likely to develop metastasis. In more than 80% of the cases UM is driven by an activating mutation in ...
Impact of ERK signaling and its spatial regulation on cisplatin sensitivity in ovarian cancer cells
(2019-11-08)
The efficiency of the anticancer drug cisplatin in ovarian cancer is often limited by the development of cisplatin resistance. Cisplatin activates a plethora of DNA damage-related signaling pathways, which regulate the ...
Statistical mechanics of gradient models
(2019-07-18)
In this thesis, we consider gradient models on the d-dimensional discrete lattice. These models serve as effective models for interfaces and are also known as continuous Ising models . The height of the interface is modelled ......
Search for Squarks and Gluinos in τ-lepton Final States with the ATLAS Experiment
(2019-09-24)
Suche nach Squarks und Gluinos in τ-Lepton Endzuständen mit dem ATLAS Experiment
Das erfolgreiche und wohletablierte Standardmodell der Teilchenphysik ist in der Lage, die Mehrheit der beobachteten ...
Das erfolgreiche und wohletablierte Standardmodell der Teilchenphysik ist in der Lage, die Mehrheit der beobachteten ...