E-Dissertationen: Search
Now showing items 71-80 of 140
Stereoselektive Polyolsynthese zur Untersuchung von Wasserstoffbrückenbindungen mittels IR-Spektroskopie
(2020-12-11)
Um die anomalen Eigenschaften des Wassers gänzlich zu verstehen, ist die intensive Untersuchung von Wasserstoffbrücken erforderlich. IR-spektroskopische Messungen vernetzter Flüssigkeiten liefern dabei eine Fülle an ...
Antiapoptotic survival strategies of human neurons
(2021-06-28)
Neurons of the central and peripheral nervous system are the key information processing and relay units within the human body. Since neurons are post-mitotic cells and neurogenesis in the adult human brain is very limited, ...
Charakterisierung zellulärer Kräfte von Mikrogeweben durch Entwicklung eines elastischen, dreidimensionalen Zellkultursystems
(2021-03-12)
Zellen sind in einem Organismus eng mit der Extrazellulären Matrix (ECM) verbunden. Die mechanischen Eigenschaften der ECM, wie die Elastizität sowie ihre Topographie sind dabei besonders entscheidend für Epithelzellen. ...
Microevolutionary processes and taxonomic investigations of the Atacama Desert flora
(2020-12-22)
Plant evolutionary processes in the hyper arid Atacama Desert of northern Chile are here investigated using our species/species complexes as case studies based on the following research questions:
(1) Are populations ......
(1) Are populations ......
Development of workflows for metabarcoding of mass-samples: A case study on Diptera
(2020-02-14)
The main goal was developing a workflow for comprehensive biodiversity monitoring using a DNA Barcoding approach. As one of the major insect groups in the Palearctic the diverse order of Diptera served as an experimental ...
Development of oligomer-specific antibodies against tau protein and testing of therapeutic potential in a cell model of tau pathology
(2020-04-15)
Tau, a microtubule associated protein, forms abnormal aggregates in many neurodegenerative diseases such as Alzheimer disease (AD). There is an urgent need for disease-modifying therapies of AD and related tauopathies. ......
Regulation des Cochaperons BAG3 durch Phosphorylierung und Dephosphorylierung
(2020-01-07)
Die Zelle ist die kleinste Organisationseinheit, aus der alle Organismen aufgebaut sind. Sie ist auf ein Gleichgewicht der Proteinausstattung, die Proteostase, angewiesen. Auch das Cytoskelett ist essentiell für die Zelle, ...
A reporter cell system for TREM2 reveals differential effects of disease-associated variants on receptor signaling and activation by antibodies against the stalk region
(2021-06-08)
The triggering receptor expressed on myeloid cells 2 (TREM2) is an immune receptor expressed on myeloid-derived cell types. The extracellular immunoglobulin-like domain of TREM2 binds anionic ligands including Apolipoprotein ...
The Role of Phytol Degradation in Chlorophyll and Tocopherol (Vitamin E) Metabolism
(2021-10-14)
The phytol degradation in the model plant Arabidopsis thaliana was studied. Phytol is the hydrophobic side of chlorophyll and is considered to be most abundant isoprenoid molecule in the biosphere. But the degradation of ...
Analysis of two selected cell wall proteins and one lncRNA involved in desiccation tolerance of the resurrection plant Craterostigma plantagineum
(2020-01-07)
Water deficit is a severe stress negatively affecting plant growth and productivity. Extreme dehydration, termed desiccation, will lead to substantial water loss from cells and eventually results in less than 10% RWC ...