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Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations: The establishment of translating ribosome affinity purification 

Zhao, Wenchao (2020-11-04)
Recoding of in-frame UGA/Seccodon in selenoproteins requires a complex translational machinery. The core of this event is the interaction between selenocysteine insertion sequence (SECIS element) in the 3’UTR of ...
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Nanoparticle delivery of molecular agents to tackle HIV latency 

Ali, Abdalla Abbas Jafer (2022-09-16)
Antiretroviral therapy (ART) effectively suppresses HIV replication in people living with HIV (PLWH), but treatment is lifelong. The persistence of long-lived, latently infected resting CD4+T cells is a significant ...
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Lipid droplet formation drives pathogenic ILC2 responses in airway inflammation 

Kharabi Masouleh, Schekufe (2020-06-08)
The Western world is affected by a dramatic increase of chronic inflammatory diseases like asthma, Crohn’s disease and psoriasis. Innate lymphoid cells (ILC) play an important role in the control and maintenance of barrier ...
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Nucleic acid sensing in CD4 T cells during HIV-1 and other viral infections 

Holz, Marvin (2021-10-15)
Viruses are small intracellular parasites and use the host cell’s biosynthesis machinery to replicate and spread. Therefore, viral particles incorporate structures that are similar to the ones that naturally occur within ...
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Investigating the ability of RIG-I agonists to provide protection in mouse and ferret models of respiratory virus infection 

Schwab, Lara Sonja Ute (2022-05-17)
Respiratory infections caused by influenza A virus (IAV) or respiratory syncytial virus (RSV) lead to substantial morbidity and mortality. Treatment options are limited and there is urgent need for the development of ......
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Control of pulmonary immunity by physical exercise 

Michla, Marcel (2024-03-06)
Sedentary lifestyles combined with high caloric nutrition are widely known to severely contribute to the rise of metabolic diseases like diabetes, atherosclerosis, or obesity in recent years. While endurance training has ......
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Inflammation-dependent differentiation of two distinct regulatory T cell populations in the visceral adipose tissue shapes systemic metabolism 

Valle Torres, Stalin Santiago (2023-12-07)
Visceral adipose tissue (VAT) is an endocrine organ critical for energy storage and metabolic homeostasis. It harbours a plethora of immune cells, which play an important role in maintaining tissue homeostasis. A large ...
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Impact of G-Quadruplexes on DNA damage and repair supported by the protein Zuo1 in Saccharomyces cerevisiae 

Limmer, Michaela Martina (2025-01-09)
The secondary structures known as G-Quadruplexes (G4s) play crucial roles in regulating biological processes such as replication, transcription, and DNA repair by folding and unfolding within specific regions of DNA. ......

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AuthorAli, Abdalla Abbas Jafer (1)Holz, Marvin (1)Kharabi Masouleh, Schekufe (1)Limmer, Michaela Martina (1)Michla, Marcel (1)Schwab, Lara Sonja Ute (1)Valle Torres, Stalin Santiago (1)Zhao, Wenchao (1)SubjectHIV (2)RIG-I (2)airway inflammation (1)Angeborene Immunität (1)angeborenes Immunsystem (1)chromatin structure (1)Chromatinstruktur (1)DNA repair (1)DNA-Reparatur (1)fatty acids (1)... View MoreClassification (DDC)
540 Chemie (8)
610 Medizin, Gesundheit (7)615 Pharmakologie, Therapeutik (5)500 Naturwissenschaften (3)570 Biowissenschaften, Biologie (3)... View MoreResource TypeDissertation oder Habilitation (8)... View MoreDate Issued2020 (2)2022 (2)2021 (1)2023 (1)2024 (1)2025 (1)

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