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The primary cilium is a unique lipid microdomain engineered to transduce extracellular cues
(2022-04-06)
Cilia are membrane protrusions located at the surface of almost every vertebrate cell. Cilia come in two different flavors: motile cilia, which generate a fluid flow or propel cells for active movement, and immotile, also ...
Elucidating cyclic AMP signaling in subcellular domains with optogenetic tools and fluorescent biosensors
(2019-11-14)
The second messenger 3´, 5´-cyclic nucleoside adenosine monophosphate (cAMP) plays a key role in signal transduction across prokaryotes and eukaryotes. Cyclic AMP signaling is compartmentalized into microdomains to fulfil ...