Fakultäten der Universität Bonn: Suche
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Between Town and Monastery: Peasant economy in the first millennium AD
(2021-11-16)
Approaches to early medieval peasantry are often polarized, either enhancing the benefits brought by the weakening of aristocratic dominance or emphasizing the limited prospects for peasant development in the absence of a ...
Minimisation problems in continuum mechanics and generalised convex hulls
(2022-11-24)
The goal of this thesis is the analysis of functionals subject to a differential constraint. These functionals appear in minimisation problems which are connected to problems coming from continuum mechanics. In the ...
Genetic variations in root architecture traits for water and nitrogen use efficiency in wheat and barley
(2022-11-24)
The soil edaphic resources such as water and nitrogen are essential for crop production because they are required by plants for proper growth and tissue development. The global crop production is vulnerable due to rapid ...
Evolution and genetic basis of pelvic-brooding, a derived reproductive strategy in Sulawesi ricefishes (Beloniformes: Adrianichthyidae)
(2022-11-04)
In Sulawesi ricefishes (Adrianichthyidae, Beloniformes) a derived reproductive strategy evolved. It is unique in the way that females of pelvic brooding species carry the eggs for up to 18 days until the fry hatches outside ......
Translatome analysis and in vivo Ca2+ imaging of astrocytes in an Alzheimer’s disease mouse model
(2021-03-18)
One of the most prominent hallmarks of Alzheimer’s Disease (AD) is the accumulation of amyloid beta (Abeta) species, which have the tendency to form extracellular insoluble Abeta plaques and induce reactive astrogliosis ...
Options to improve irrigation efficiency and productivity under rotational delivery schedule, a bottom-up approach applied at canal irrigation scheme in Pakistan
(2022-12-06)
In Punjab, Pakistan, the Warabandi principle guides the distribution of surface water over a network of canals providing farmers with limited water in proportion to land size in a fixed 7-days rotation. Current problems ...
Regulation of inflammasome activation: roles for phospholipase C and mitochondria
(2021-08-05)
Inflammasomes are protein complexes serving as activation platforms for the protease caspase-1, which leads to a pro-inflammatory type of cell death termed pyroptosis and to maturation and release of the cytokines interleukin- ......
Investigating the ability of RIG-I agonists to provide protection in mouse and ferret models of respiratory virus infection
(2022-05-17)
Respiratory infections caused by influenza A virus (IAV) or respiratory syncytial virus (RSV) lead to substantial morbidity and mortality. Treatment options are limited and there is urgent need for the development of ......
I) Characterization of LytR-CpsA-Psr enzymes and their role in Staphylococcus aureus cell wall formation
II) Elucidating the mode of action of Cacaoidin, a novel class V lantibiotic
(2022-04-04)
Antibiotic resistance poses a serious threat to human health, demanding for the discovery and development of antibiotics with resistance-breaking properties. New antibiotics should be sought with the focus on novel chemistry ...
Design and Synthesis of A2B- and Dual-Acting A2A/A2B Adenosine Receptor Antagonists
(2020-10-27)
A2A and A2B adenosine receptors (ARs) are novel drug targets in cancer (immuno)therapy. Activation of A2AARs expressed on the surface of many immune cells such as T-lymphocytes and natural ...