Life & Medical Sciences-Institut (LIMES)

 

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  • Fetal liver macrophages contribute to the hematopoietic stem cell niche by controlling granulopoiesis 

    Kayvanjoo, Amir Hossein; Splichalova, Iva; Bejarano, David Alejandro; Huang, Hao; Mauel, Katharina; Makdissi, Nikola; Heider, David; Tew, Hui Ming; Balzer, Nora Reka; Greto, Eric; Osei-Sarpong, Collins; Baßler, Kevin; Schultze, Joachim L.; Uderhardt, Stefan; Kiermaier, Eva; Beyer, Marc; Schlitzer, Andreas; Mass, Elvira (2024-03-25)
    During embryogenesis, the fetal liver becomes the main hematopoietic organ, where stem and progenitor cells as well as immature and mature immune cells form an intricate cellular network. Hematopoietic stem cells (HSCs) ...

  • Fate-Mapping of Yolk Sac-Derived Macrophages 

    Splichalova, Iva; Mass, Elvira (2023-08-29)
    To better understand the distinct functions of yolk-sac-derived tissue-resident macrophages (TRMs) and bone-marrow-derived macrophages in homeostasis and disease, it is important to trace the ontogeny of these cells. The ...

  • Fate-Mapping of Hematopoietic Stem Cell-Derived Macrophages 

    Mauel, Katharina; Mass, Elvira (2023-08-29)
    Macrophages are cells of the innate immune system, which contribute to the maintenance of tissue homeostasis and form the first line of defense against pathogens. Tissue-resident macrophages that originate from ...

  • Replicability and reliability of the background and target velocity effects in smooth pursuit eye movements 

    Schröder, Rebekka; Baumert, Philine Margarete; Ettinger, Ulrich (2021-07-07)
    When we follow a slowly moving target with our eyes, we perform smooth pursuit eye movements (SPEM). Previous investigations point to significantly and robustly reduced SPEM performance in the presence of a stationary ...

  • Fetal-Derived Immune Cells at the Roots of Lifelong Pathophysiology 

    Maas, Elvira; Gentek, Rebecca (2021-02-23)
    Tissue-resident innate immune cells exert a wide range of functions in both adult homeostasis and pathology. Our understanding of when and how these cellular networks are established has dramatically changed with the ...