Mathematisch-Naturwissenschaftliche Fakultät: Auflistung Mathematisch-Naturwissenschaftliche Fakultät nach Titel
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Innovative analytical tools in the biopharmaceutical development: Applying SPR/Biacore, calorimetry and light scattering methods to the study of interactions between anticancer antibodies and the EGFR
Alvarenga, Maria Leonor Mendes Godinho de (2010-12-08)Targeting of the epidermal growth factor receptor (EGFR) has become an established antitumor strategy with anti-EGFR antibodies approved for clinical use or in late stages of development. Postulation of antibody effector ... -
Innovative Pharmaceutical Stabilization and Formulation Techniques for Protein Drugs
Dauer, Katharina (2023-12-18)Solid protein formulations for peroral, nasal or parenteral administration would significantly improve the therapeutic use, compliance, and stability of protein-based drugs. The aim of this work was to develop, apply, and ... -
Innovative Pulsar Searching Techniques: or Fantastic Pulsars and How to Find Them
Cameron, Andrew David (2018-06-14)Pulsars are rapidly rotating, highly magnetised neutron stars which emit beams of electromagnetic radiation from their magnetic poles, most commonly in the radio spectrum. These massive and extremely compact objects have ... -
Innovative Therapiekonzepte in mesenchymalen Neoplasien
Ihle, Michaela A. (2015-10-09)Sarkome sind eine Gruppe heterogener Tumore, deren Therapieoptionen überwiegend in konventioneller Chemo- oder Strahlentherapie bestehen. Ansätze einer personalisierten Medizin sind nur bei wenigen Subentitäten etabliert. ... -
Insights into Biomolecular Structure from Theoretical Spectroscopy
Riplinger, Christoph (2011-11-29)The first part of the present PhD thesis is concerned with the reaction mechanism of Cytochrome P450 NO reductase. Two important aspects of this enzyme are studied. 1) The structural and electronic nature of the key ... -
Insights into function of transcription factor Ap-2δ: target genes and interaction partners
Hesse, Katrin (2012-03-12)The Ap-2 transcription factors comprise a family of sequence-specific DNA-binding proteins that play pivotal roles in regulating gene expression during development, differentiation, and tumorigenesis.
According to ... -
Insights into high-temperature mineral reactions of calcium silicate materials revealed in operando by in situ Raman spectroscopy
Böhme, Nadine Susanne (2022-11-30)Knowledge of high-temperature calcium silicate materials is becoming increasingly interesting for industry in different ways. On the one hand, their application in the construction, cement, refractory, and ceramics industry ... -
Insights into the molecular adaptation of Staphylococcus aureus to copper Schiff´s base at proteome level
Kaveeshwar, Vishwas (2017-09-21)The molecular adaptation of S.aureus to copper Schiff’s base (CSB) was studied by comparative proteome analysis. Proteome analysis was performed by employing nano LC-MALDI mass spectrometry with isobaric tags (iTRAQ) and ... -
Instabilities in the envelope of stars
Grassitelli, Luca (2016-12-22)Stars shine, id est they release energy from their surfaces. This energy is mostly provided by thermonuclear fusion in their cores, and has thus to be transported through the whole star. Especially in the low density outer ... -
Integrated hydrologic modeling as a key for sustainable development planning of urban water resources in the semi-arid watersheds of the Gaza Strip
Eshtawi, Tamer (2015-07-21)This study demonstrates the strength of using integrated hydrologic modeling in a sustainable urban water planning process. It provides a complete view of the urban water system of the Gaza Strip, quantifies the urban water ... -
An Integrated Remote Sensing and Urban Growth Model Approach to Curb Slum Formation in Lagos Megacity
Badmos, Olabisi Sakirat (2019-04-05)Rapid urbanization with limited development has led to slum proliferation in many sub-Saharan African cities. Slums are recognized as a menace to planned cities, as they do not conform to planning standards, thus the need ... -
Integrated structural biology investigation of the bacterial TRAP transporter SiaPQM from pathogenic bacteria
Glänzer, Janin (2023-10-31)Sialic acid is utilized by human pathogens like Vibrio cholerae in various ways to colonize the host. Upon contamination it scavenges the sialic acid from mucus-rich parts of the body such as the gut and causes ... -
Integrated terrestrial simulations at the continental scale: Impact of groundwater dynamics and human water use on groundwater-to-atmosphere feedbacks during the European heatwave in 2003
Keune, Jessica (2019-02-19)The availability of freshwater under current and future climatic conditions remains one of the main research topics that requires an improved understanding of the terrestrial system and anthropogenic impacts. Yet, hydrologic ... -
Integrated Terrestrial Simulations over Europe: Groundwater-Atmosphere Feedbacks with Altered Water Tables Including the Effect of Recent Droughts
Hartick, Carl Martin (2023-08-08)The groundwater flow is an essential part of the terrestrial system encompassing the atmosphere, land surface, and subsurface. In past research, there was usually no focus on water in the subsurface because climate models ... -
Integrating Existing Object-Oriented Databases with Distributed Object Management Platforms: Developed and evaluated on the example of ODBMS ObjectStore and CORBA
Shumilov, Sergey (2003)A common characteristic of today's information systems is the distribution of data among a number of autonomous systems and heterogeneous repositories. The key to their unification is the ability to access these multiple ... -
Integrating the Pharmacist into Cancer Medication Management
Döhler geb. Reineking, Nele (2012-01-06)Aim: The present study aimed at evaluating the integration of the pharmacist in multiprofessional cancer care.
Methods: Part I: Two pharmaceutical care services for cancer patients were compared. One was provided ... -
Integration of Data Mining into Scientific Data Analysis Processes
Wegener, Dennis (2012-12-13)In recent years, using advanced semi-interactive data analysis algorithms such as those from the field of data mining gained more and more importance in life science in general and in particular in bioinformatics, genetics, ... -
Integrative Systems Approaches Towards Brain Pharmacology and Polypharmacology
Shahid, Mohammad (2014-05-02)Polypharmacology is considered as the future of drug discovery and emerges as the next paradigm of drug discovery. The traditional drug design is primarily based on a “one target-one drug” paradigm. In polypharmacology, ... -
Intensitäts- und Energieerhöhung an ELSA
Schedler, Manuel (2015-12-04)An der Elektronen-Stretcher-Anlage ELSA am Physikalischen Institut der Universität Bonn werden im Zuge des Sonderforschungsbereichs SFB/TR 16 “Elektromagnetische Anregung subnuklearer Systeme” Experimente zur Untersuchung ... -
(Inter-)nationale Klimapolitik und die Produktion des Raumes: Eine qualitative Fallstudie zu REDD+ in Kapuas, Zentral-Kalimantan, Indonesien
von Werder, Saskia Antonia (2016-12)The present master thesis analyzes REDD+, a market-based climate mitigation instrument designed by the UNFCCC to reduce and prevent carbon dioxide emissions from tropical regions. The analysis presented hereafter aims at ...