Oncolytic virus therapy (OVT) is emerging as a potent alternative to conventional cancer treatments by employing engineered viruses that selectively infect and lyse tumor cells while sparing normal tissues. Although ...

Organoids have rapidly matured into powerful model systems. The field is pushing organoids toward architectural sophistication and functional fidelity, with longitudinal experiments producing ever-larger and more complex ...

This thesis considers four search problems which are related to or emerge from a geometric context. Each search problem is examined in a separate chapter; these four chapters are framed by an introduction and a conclusion ...

Mathematical models are in focus of modern systems biology and increasingly important to understand and manipulate complex biological systems. At the same time, new and improved techniques in metabolomics and proteomics ...

Diese Arbeit befasst sich mit Dünngitterverfahren zur Lösung von höherdimensionalen Problemen. Sie zeigt drei neue Aspekte von Dünnen Gittern auf: Erweiterungen der elementaren Werkzeuge zur Arbeit mit Dünnen Gittern, eine ...

Zur Untersuchung der Knochenumbauvorgänge sind neben klinischen auch biomechanische Methoden, die den Hauptgegenstand der vorliegenden Arbeit bilden, von besonderer Bedeutung. Insbesondere numerische Simulationen der ...