Bei der Erforschung von Materie hat man sich in der Geschichte schrittweise, durch Beobachtungen und Modelle, an ihre untergeordneten Strukturen herangetastet. Aus heutiger Sicht sind Quarks und Gluonen, neben den Elektronen, ...

The navigation of precursor cells of inhibitory interneurons from their germinal zone inside the fourth ventricle through the white matter towards their final destination within the cerebellum's molecular layer is an ongoing ...

Mathematical models are in focus of modern systems biology and increasingly important to understand and manipulate complex biological systems. At the same time, new and improved techniques in metabolomics and proteomics ...

Infectious disease modeling faces an inherent tension between physical realism and computational feasibility. Granular metapopulation models offer interpretability and the capacity to resolve complex behavioral dynamics ......

Organoids have rapidly matured into powerful model systems. The field is pushing organoids toward architectural sophistication and functional fidelity, with longitudinal experiments producing ever-larger and more complex ...

Diese Arbeit befasst sich mit Dünngitterverfahren zur Lösung von höherdimensionalen Problemen. Sie zeigt drei neue Aspekte von Dünnen Gittern auf: Erweiterungen der elementaren Werkzeuge zur Arbeit mit Dünnen Gittern, eine ...

This thesis considers four search problems which are related to or emerge from a geometric context. Each search problem is examined in a separate chapter; these four chapters are framed by an introduction and a conclusion ...

Zur Untersuchung der Knochenumbauvorgänge sind neben klinischen auch biomechanische Methoden, die den Hauptgegenstand der vorliegenden Arbeit bilden, von besonderer Bedeutung. Insbesondere numerische Simulationen der ...

Oncolytic virus therapy (OVT) is emerging as a potent alternative to conventional cancer treatments by employing engineered viruses that selectively infect and lyse tumor cells while sparing normal tissues. Although ...

The estimation of unknown parameters is a key step in the development of mechanistic dynamical models for biological processes. While quantitative measurements are typically used for model calibration, in many applications, ...