This thesis focuses on developing mathematical models utilizing complex biomedical datasets to understand epidemiological and cell-biological processes. The thesis is divided into three primary research articles and addresses ...

Infectious disease modeling faces an inherent tension between physical realism and computational feasibility. Granular metapopulation models offer interpretability and the capacity to resolve complex behavioral dynamics ......

The navigation of precursor cells of inhibitory interneurons from their germinal zone inside the fourth ventricle through the white matter towards their final destination within the cerebellum's molecular layer is an ongoing ...

Oncolytic virus therapy (OVT) is emerging as a potent alternative to conventional cancer treatments by employing engineered viruses that selectively infect and lyse tumor cells while sparing normal tissues. Although ...

Organoids have rapidly matured into powerful model systems. The field is pushing organoids toward architectural sophistication and functional fidelity, with longitudinal experiments producing ever-larger and more complex ...

Zur Untersuchung der Knochenumbauvorgänge sind neben klinischen auch biomechanische Methoden, die den Hauptgegenstand der vorliegenden Arbeit bilden, von besonderer Bedeutung. Insbesondere numerische Simulationen der ...