This thesis focuses on developing mathematical models utilizing complex biomedical datasets to understand epidemiological and cell-biological processes. The thesis is divided into three primary research articles and addresses ...

Exponential advancements in computer technology over the last five decades have ubiquitously benefited science and humanity as a whole. Consequent beneficiaries of this surge of computational power include all subfields ......

The field of systems biology makes an attempt to realise various biological functions and processes as the emergent properties of the underlying biochemical network model. The area of computational systems biology deals ...

The navigation of precursor cells of inhibitory interneurons from their germinal zone inside the fourth ventricle through the white matter towards their final destination within the cerebellum's molecular layer is an ongoing ...

Mathematical models are in focus of modern systems biology and increasingly important to understand and manipulate complex biological systems. At the same time, new and improved techniques in metabolomics and proteomics ...

Tissue dynamics are complex and involve interactions between different cell types and extracellular components on different spatial and temporal scales. Specific tissue properties are relevant for a broad range of processes, ...