Institut für Rekonstruktive Neurobiologie (IRN)

The impact of the mesoprefrontal dopaminergic system on the maturation of interneurons in the murine prefrontal cortex
Islam, K. Ushna S.; Blaess, Sandra (2024-07-05)
The prefrontal cortex (PFC) undergoes a protracted maturation process. This is true both for local interneurons and for innervation from midbrain dopaminergic (mDA) neurons. In the striatum, dopaminergic (DA) neurotransmission ...
The missense mutation C667F in murine β-dystroglycan causes embryonic lethality, myopathy and blood-brain barrier destabilization
Tan, Rui Lois; Sciandra, Francesca; Hübner, Wolfgang; Bozzi, Manuela; Reimann, Jens; Schoch, Susanne; Brancaccio, Andrea; Blaess, Sandra (2024-06-18)
Dystroglycan (DG) is an extracellular matrix receptor consisting of an α- and a β-DG subunit encoded by the DAG1 gene. The homozygous mutation (c.2006G>T, p.Cys669Phe) in β-DG causes muscle-eye-brain disease with multicystic ...