bonndoc - Der Publikationsserver der Universität Bonn: Recent submissions
Now showing items 1-20 of 7575
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Modelling Complex Activities from Visual and Textual Data
(2021-07-23)Complex activity videos are long-range videos composed of multiple sub-activities following some temporal structuring and connected purpose. Recognizing human activities in such videos is a long-standing goal with a broad ... -
Archive des Verborgenen: Vorgeschichte und Gegenwart in der Literatur um 1800
(2021-07-23)Im 18. Jahrhundert tritt das Subjekt in den Mittelpunkt der Wahrnehmung. Seine Entwicklung wird literarisch im Bildungsroman dargestellt. Wissen und Bildung werden zunehmend zur Grundlage der Gestaltung einer Zukunft. Von ... -
Bedarfs- und Krankheitskostenanalyse der stationärenund ambulanten Betreuung von Patienten mit Kurzdarmsyndrom
(2021-07-23)Hintergrund und Fragestellung: Die Erkrankung Kurzdarmsyndrom (KDS) wird zu den seltenen Erkrankungen gezählt. Es bezeichnet entsprechend der S3-Leitlinie der Deutschen Gesellschaft für Ernährungsmedizin ... -
Evolution of the Activity Cliff Concept and Practical Implications for Compound Design
(2021-07-22)Entering the “big data” era, a number of different research areas have witnessed an enormous increase in data at an exponential rate. For drug discovery, various publicly available protein structure and compound bioactivity ... -
Electrostatic anchoring of SNAP25 to the plasma membrane
(2021-07-21)Neurotransmission is based on incredibly rapid membrane trafficking cycles, mediating the release of neurotransmitters. The fusion machinery of the well-studied SNARE protein complex ensures the speed and precision of ... -
Deciphering the functional role of the LIS1/NDEL1/14.3.3ε protein complex in the expansion of human cortical progenitors in an iPSC-derived organoid model
(2021-07-19)The human brain is an exceptionally complex organ, both structurally and functionally, and represents the most remarkable progress in evolution. The human cortex is a highly organised and extensively folded structure ... -
External Spanier-Whitehead duality for C-spectra and applications to C-homology theories
(2021-07-19)The thesis constructs a Spanier-Whitehead type duality functor relating finite C-spectra to finite Cop-spectra, where C is a topological index category. We prove that every C-homology theory is given by taking the homotopy ... -
Investigation of the procoagulant role of labile heme under hemolytic conditions
(2021-07-19)Severe intravascular hemolysis leads to the excessive release of labile heme into the vascular compartment, thereby overwhelming the heme-binding capacity of the protective heme- scavenging system. As a consequence, labile ... -
Analyse von periplasmatischen Schwefeltransferasen aus Allochromatium vinosum
(2021-07-19)Die ersten Schritte der Schwefeloxidation in Allochromatium vinosum finden im Periplasma statt, wo reduzierte Schwefelverbindungen oxidiert und in diesem Zuge Schwefelkugeln aufgebaut werden. Es ist denkbar, dass ... -
Vertex Algebras and Factorization Algebras
(2021-07-19)This thesis is about the relationship between vertex algebras and Costello-Gwilliam factorization algebras, two mathematical approaches to chiral conformal field theory. Many vertex algebras have already been constructed. ... -
Hyperbolic and dispersive singular stochastic PDEs
(2021-07-19)The purpose of this thesis is to analyse nonlinear Schrödinger and wave equations which have been perturbed by a singular stochastic potential. The tools are, on the one hand, paracontrolled calculus, and, on the other ... -
Essays in Applied Microeconomics
(2021-07-19)Two topics are covered in this dissertation. One topic is about individual's contribution decisions in social dilemmas situations (situations, when everyone is better off keeping their endowments for themselves but everybody ... -
Effect of osmotic stress on barley leaf cuticles
(2021-07-19)Assessing the drought stress tolerance at the seedling stage is an important trait as it later affects the growth and grain yield. The leaf and root characteristics are mainly focused on during this seedling stage. The ... -
Freies Handeln
(2021-07-15)Diese Arbeit befasst sich mit dem Problem der Freiheit im Rahmen der neueren Ansätze der analytischen Philosophie im weitesten Sinne. Der Untersuchung liegt die These zugrunde, dass die menschliche Freiheit tief im Handeln ... -
Investigation of SECISBP2 mutations and potential viral SECIS element recruitment
(2021-07-15)The 21st amino acid selenocysteine (Sec) is encoded by the UGA codon. In order to recode the canonical stop codon additional factors are needed in mammals including the selenocysteine-insertion-sequence (SECIS) ... -
Super-resolution time-resolved imaging using computational sensor fusion
(2021-01-18)Imaging across both the full transverse spatial and temporal dimensions of a scene with high precision in all three coordinates is key to applications ranging from LIDAR to fluorescence lifetime imaging. However, compromises ... -
Extracellular vesicles derived from Hepatitis-D Virus infected cells induce a proinflammatory cytokine response in human peripheral blood mononuclear cells and macrophages
(2020-02-14)Hepatitis D Virus (HDV) is a satellite virus requiring a Hepatitis B Virus (HBV) envelope proteins for productive infection. Hepatitis D is the most severe form of viral hepatitis and is a global health threat affecting ... -
Neuroinvasion and cerebral ischemia as possible sources for α-synuclein prions in Parkinson’s disease
(2021-07-13)(noch nicht zugänglich / not yet accessible) -
Implementation of the novel high-throughput Fungal Isolation one step Device method FIND and secondary metabolite extraction from the isolate Heydenia cf. alpina
(2021-07-13)Fungi are an important source of bioactive metabolites. The cultivation of source organisms is a crucial step in natural product isolation. With standard isolation methods for fungi it is difficult to isolate rare und ... -
Low molecular weight polysialic acid prevents lipopolysaccharide-induced inflammatory dopaminergic neurodegeneration in humanized SIGLEC11 transgenic mice
(2021-07-13)Parkinson’s disease is one of the most common neurodegenerative diseases in the elderly population, with a pathophysiology linked to neuroinflammation, complement activation and oxidative damage. Soluble polysialic acid ...
