Auflistung nach Autor "Paeschke, Katrin"
Anzeige der Dokumente 1-6 von 6
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The DEAH helicase DHX36 and its role in G-quadruplex-dependent processes
(2020-10-12)<em>DHX36</em> is a member of the DExD/H box helicasefamily, which comprises a large number of proteinsinvolved in various cellular functions. Recently, thefunction of DHX36 in the regulation of G-quadruplexes(G4s) was ... -
Functions of the DEAH-box helicase DHX36 in type I interferon signaling
(2023-01-06)The induction of type I interferons (IFN) is a hallmark of foreign nucleic acids immune sensing by the innate immune system. Based on the universal molecular structure of DNA and RNA throughout all kingdoms of life, the ... -
G-quadruplex formation in mouse macrophages changes the immune response to bacterial infection
(2024-01-03)G-quadruplexes (G4s) are stable secondary structures that form in guanine-rich regions of DNA and RNA. Guanines bind via Hoogsteen hydrogen bonding and form G tetrads that stack upon each other and become stabilized by a ... -
Impact of G-Quadruplexes on DNA damage and repair supported by the protein Zuo1 in Saccharomyces cerevisiae
(2025-01-09)The secondary structures known as G-Quadruplexes (G4s) play crucial roles in regulating biological processes such as replication, transcription, and DNA repair by folding and unfolding within specific regions of DNA. ... -
The influence of G-quadruplex structures on meiosis
(2021-01-27)Several lines of evidence emphasize the potential function of G-quadruplex (G4) structures during DNA replication, transcription and recombination. Although there are experimental evidences that G4s play a role during ... -
Understanding telomere dynamics with G-quadruplex secondary structures in S. cerevisiae
(2022-03-10)Telomeres are specialized nucleoprotein structures at the end of linear eukaryotic chromosomes, vital for safeguarding of genetic material. They inhibit nucleolytic degradation, end to end fusion and unwanted recombination. ...
