Auflistung nach Schlagwort "T Zellen"
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Aptamers for targeted activation of T cell-mediated immunity
Haßel, Silvana Katharina (2016-09-19)An attractive way of preventing or curing infections and diseases is to mobilize patient’s own defense mechanisms, the immune system. Treatments following this approach are commonly known as immunotherapies. The development ... -
Investigations on centrosomes, their function and regulation during immune synapse formation
Weier, Ann-Kathrin (2022-01-24)The centrosome is a cellular organelle well known for its function during cell division. It consists of two centrioles that are formed by microtubules and surrounded by a multiprotein matrix the so-called pericentriolar ... -
Return of the first inflammasome: Elucidation of NLRP1 inflammasome activation by p38-mediated phosphorylation and ubiquitination
Jenster, Lea-Marie (2024-01-30)The assembly of inflammasomes is linked to the detection of pathogens and other danger signals by intracellular pattern-recognition receptors of the mammalian innate immune system. The human inflammasome sensor NLRP1 is ...