Fakultäten der Universität Bonn: Suche
Anzeige der Dokumente 121-130 von 395
SRPK2 regulates active zone ultrastructure and RIM1 phosphorylation to tune presynaptic function and plasticity
(2020-07-30)
Chemical synapses communicate through the release of neurotransmitter-filled synaptic vesicles into the synaptic cleft. Synapses are able to dynamically adapt to the changes in the neuronal network by strengthening or ...
Aktivierung des angeborenen Immunsystems im Zentralnervensystem nach subchronischer Alkoholbehandlung im Mausmodell
(2020-06-03)
Alkohol ist als kulturell anerkanntes Rauschmittel in seinen ökonomischen, sozialen und gesundheitlichen Risiken weiterhin unterschätzt. In der Literatur zeigen sich Hinweise auf die Relevanz unterschiedlicher Trinkmuster ...
Outcome von Krebspatienten ausländischer und deutscher Nationalität am Centrum für Integrierte Onkologie Bonn: Eine Matched-Pair-Analyse
(2020-11-05)
Ziel der Matched-Pair-Analyse war es, potenzielle Unterschiede im Therapieansprechen und Überleben von Krebspatienten ausländischer und deutscher Nationalität, die zwischen Januar 2010 und Juni 2016 am Centrum für Integrierte ...
Totalsynthesen neuartiger Leupylogs: vereinfachte Strukturanaloga der Leupyrrine
(2020-06-03)
Die vorliegende Dissertation behandelt die totalsynthetische Darstellung von neuartigen Strukturanaloga der Leupyrrine. Diese Stoffklasse myxobakterieller Sekundärmetabolite zeichnet sich durch die Kombination einzigartiger ......
Total Synthesis of novel Leupylogs – simplified Structural Analogues of Leupyrrins
This submitted thesis deals with the development of the total synthesis of novel Leupylogs, structural leupyrrin ......
Total Synthesis of novel Leupylogs – simplified Structural Analogues of Leupyrrins
This submitted thesis deals with the development of the total synthesis of novel Leupylogs, structural leupyrrin ......
Federated Query Processing over Heterogeneous Data Sources in a Semantic Data Lake
(2020-05-05)
Data provides the basis for emerging scientific and interdisciplinary data-centric applications with the potential of improving the quality of life for citizens. Big Data plays an important role in promoting both manufacturing ...
Broken Roads and Broken Laws: How Infrastructure and Law Enforcement Shape Amazonian Deforestation Frontiers
(2020-06-29)
Deforestation of tropical rainforests contributes significantly to global climate change and accelerated biodiversity loss. To mitigate these impacts, the goal of drastically reducing tropical deforestation has been a ...
The role of the endocannabinoid system in stress-related disorders and neuroimmune communication
(2020-05-04)
In the last decades, increasing evidence suggests that inflammatory processes play an important role in the development of psychiatric disorders, such as anxiety and depression. Psychosocial stress – one of the main ...
Investigating the neural circuitry of the Mushroom body calyx in Drosophila melanogaster
(2020-07-15)
In Drosophila melanogaster, the mushroom body (MB) is essential for the formation and retrieval of olfactory associative memories. Within its input region, the MB calyx, olfactory information is delivered from second order ...
Propagation of Tau pathology in Alzheimer disease
(2020-09-10)
Clinical and experimental evidences suggest that the spreading of tau protein throughout the brain may underlie the stereotypical progression of pathology in the brains of Alzheimer disease (AD) patients and concomitant ...
Diagnosing and managing zinc and boron deficiencies in emerging crop production systems of Nepal
(2020-12-02)
The productivity and sustainability of the prevailing crop production systems are being challenged throughout the Indo-Gangetic Plains. Limiting water resources, depletion of soil fertility, social changes and economic ...