Fakultäten der Universität Bonn: Suche
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Functional analysis of the endocannabinoid system in conditional mouse mutants
(2020-09-04)
In the scope of this thesis conditional knockout mice with a cell-specific deletion of Dagla (diacylglycerol lipase alpha) in neurons, astrocytes or microglia cells were generated, in order to identify the cellular source ...
Aufklärung des zentralen Kohlenstoff- und Energiemetabolismus des Darmbakteriums Prevotella copri
(2020-06-19)
Die vorliegende Arbeit befasste sich mit dem zentralen Kohlenstoff- und Energiemetabolismus von Prevotella (P.) copri, eines der relevantesten Bakterien der menschlichen Darmflora. Um zu verstehen, wie die Prädominanz ......
Langerhans and inflammatory dendritic epidermal cells in atopic dermatitis tolerate Toll-like receptor 2-specific activation
(2021-01-26)
Atopic dermatitis (AD) is a chronic multifactorial inflammatory skin disease. The skin of AD patients shows a significant dysbalance of the microbiome with high colonization of S. aureus, which positively correlates with ...
State-dependent processing of Dentate Gyrus granule cell activity in-vivo
(2020-12-16)
The ability to form dissimilar neural activity patterns from similar sensory driven inputs is a phenomenon found in all vertebrates, called pattern separation. In mammals, pattern separation is closely related to a subregion ...
The influence of G-quadruplex structures on meiosis
(2021-01-27)
Several lines of evidence emphasize the potential function of G-quadruplex (G4) structures during DNA replication, transcription and recombination. Although there are experimental evidences that G4s play a role during ......
Effect of neural ablation of sphingosine-1-phosphate lyase (SGPL1) in glial cells
(2021-11-24)
Sphingosine-1-phosphate (S1P) is an evolutionarily conserved catabolic intermediate of sphingolipid metabolism that regulates diverse biological processes in the brain, including neural development, differentiation, and ...
Intestinal integrity characteristics of growing pigs in response to oregano essential oil supplementation
(2021-09-06)
The production of protein of animal origin is of great importance worldwide. In Germany, pig production is of considerable importance to meet this need. To ensure successful animal production, an intact intestinal tract ...
Die Phyllosphäre als Lebensraum für Bakterien: Mechanismen der Interaktion epiphyller Bakterien mit der pflanzlichen Kutikula
(2020-12-16)
Die Phyllosphäre stellt einen lebensfeindlichen Lebensraum dar. Jedoch gibt es epiphytisch lebende Bakterien, die diesen Lebensumständen entgegenwirken und Mechanismen entwickelt haben, in diesem kargen Lebensraum Nährstoffe ......
Analyzing the Role of CyFIP2 in the Mouse Brain
(2020-06-19)
An important regulator of neuron outgrowth, growth cone motility and dendritic spine formation is the actin nucleator ARP2/3, a protein complex that functions in forming branched actin networks. ARP2/3 complex activity is ...
Combining Fluorescence and Reflectance to Quantify Dynamics in Photosynthetic Regulation
(2021-12-14)
Photosynthesis in the field is anything but steady-state. Because environment is changing, understanding plant’s photosynthetic activity in situ is challenging. Measurement of solar-induced fluorescence (SIF), along with ......