Faculties of University Bonn: Search
Now showing items 81-84 of 84
Translatome analysis and in vivo Ca2+ imaging of astrocytes in an Alzheimer’s disease mouse model
(2021-03-18)
One of the most prominent hallmarks of Alzheimer’s Disease (AD) is the accumulation of amyloid beta (Abeta) species, which have the tendency to form extracellular insoluble Abeta plaques and induce reactive astrogliosis ...
Regulation of inflammasome activation: roles for phospholipase C and mitochondria
(2021-08-05)
Inflammasomes are protein complexes serving as activation platforms for the protease caspase-1, which leads to a pro-inflammatory type of cell death termed pyroptosis and to maturation and release of the cytokines interleukin- ......
Characterization of the pro-inflammatory activity of short-chain fatty acids (SCFAs)
(2021-10-13)
Short-chain fatty acids (SCFAs), which are mainly derived from microbial fermentation of dietary fibres, have been considered to be beneficial to gut health for decades. Recently, a few of studies reported that some patients ...
The chromatin organizer Satb1 regulates the differentiation into CD4+ TH subsets and is essential for the development of TH17 cells
(2021-06-04)
CD4+ T cells play a critical role in host defense and tissue homeostasis. Upon encountering their specific antigen, naive CD4+ T cells can differentiate into the effector T helper (TH) subsets ...