Faculties of University Bonn: Search
Now showing items 1231-1240 of 1333
Programmed cell death regulation during Salmonella Typhimurium infections
(2024-01-18)
Programmed cell death (PCD) is a highly regulated process that is vital for the development and homeostasis of multicellular organisms. It functions as an essential mechanism to remove dispensable or unfavourable cells in ......
ESCRT in der Makrophageninfektion durch Rhodococcus equi
(2024-01-22)
(noch nicht zugänglich / not yet accessible)
Cellular and molecular defence mechanisms against Legionella infection
(2024-01-26)
The two most prevalent causes of Legionnaires’ disease are L. pneumophila and L. longbeachae. The rising incidence of the Legionnaires’ disease over the past two decades together with the increasing prevalence of L. ......
Return of the first inflammasome: Elucidation of NLRP1 inflammasome activation by p38-mediated phosphorylation and ubiquitination
(2024-01-30)
The assembly of inflammasomes is linked to the detection of pathogens and other danger signals by intracellular pattern-recognition receptors of the mammalian innate immune system. The human inflammasome sensor NLRP1 is ...
Deep Generative Modelling in Systems Medicine: From Transcriptomics Data to Drug Development
(2024-02-02)
(noch nicht zugänglich / not yet accessible)
Impact of human filarial infections on the metabolic and immunological profile and characterization of filariae-induced tropical pulmonary eosinophilia using a newly established mouse model
(2024-02-05)
(noch nicht zugänglich / not yet accessible)
Fluorescent proteins for two-photon FLIM analysis of presynaptic protein interactions
(2020-06-10)
Monitoring Förster Resonance Energy Transfer (FRET) between fluorescent proteins (FPs) fused to proteins of interest is a powerful approach to study dynamic interactions of cellular proteins in living cells. The choice of ...
Role of GluA2-containing AMPARs in Oligodendrocyte Lineage Cells
(2024-01-30)
Oligodendrocytes precursor cells (OPC), also called NG2 cells, proliferate or differentiate into myelin-producing oligodendrocytes throughout life. Myelination depends on neuronal activity. Although NG2 cells receive ...
Function of Cytoplasmic FMR1-interacting protein 2 (CYFIP2) in spinal motor neuron morphology during mouse embryonic development
(2022-06-03)
The development of the nervous system is a tightly regulated spatio-temporal process that involves actin cytoskeletal dynamics. The remodelling of the neuronal cytoskeleton is important for dendritic and axonal guidance, ...
The chromatin organizer Satb1 regulates the differentiation into CD4+ TH subsets and is essential for the development of TH17 cells
(2021-06-04)
CD4+ T cells play a critical role in host defense and tissue homeostasis. Upon encountering their specific antigen, naive CD4+ T cells can differentiate into the effector T helper (TH) subsets ...