Fakultäten der Universität Bonn: Suche
Anzeige der Dokumente 1261-1270 von 1327
Recognition of orthoflaviviral RNA in mosquitoes and viral countermeasures
(2024-02-26)
Various infectious diseases are caused by mosquito-borne orthoflaviviruses affecting people worldwide. Efficient transmission of these viruses highly depends on the pathogen’s ability to overcome the host immune system. ...
Etablierung eines validierten Verfahrens zur Bestimmung der Effektstärke von Sorten und Aussaatstärke auf die Blattwinkelverteilung von Weizen
(2024-02-26)
Die Blattwinkelverteilung ist ein wichtiger phänotypischer Parameter von Pflanzen, welcher die Lichtabsorption und somit auch das Wachstum und die Ertragsmenge von Nutzpflanzen beeinflusst. Eine Bestimmung der Blattwinke ...
On the enigmatic mechanism of signal transduction of "arrestin-biased" angiotensin peptides: spotlight on endogenous angiotensin 1-7
(2024-02-27)
(noch nicht zugänglich / not yet accessible)
Home range and ecology of a palaearctic lacertid: Combining novel and old approaches to assess Lacerta agilis LINNAEUS, 1758 in the centre of its distribution with considerations for conservation
(2024-02-28)
Effective species conservation requires a thorough understanding of a species’ ecology as it reveals the requirements a species has of its environment. In this thesis I combine established methods like visual encounter ......
Large scale in vivo recordings of dentate gyrus granule cells during trace eyeblink conditioning
(2024-02-29)
(noch nicht zugänglich / not yet accessible)
The Role of High-Salt Diet on Melanoma Growth
(2024-03-04)
Cutaneous melanoma is one of the most aggressive cancer types in Western countries with a rising incidence over the last decades. Treatment of early-diagnosed melanoma constitutes a good survival rate and recovery. However, ...
Immune activation by DNA sensors in ANCA associated vasculitis
(2024-03-04)
Anti-neutrophilic cytoplasmatic antibody (ANCA) associated vasculitis (AAV) is a group of rare inflammatory autoimmune diseases primarily affecting the small vessels of kidney and lung. Current treatment options mainly ...
Charakterisierung des mitochondrialen Stresssensors Pink1 während der Mitophagie
(2024-03-08)
Die vorliegende Arbeit beschäftigt sich mit der zentralen Frage der Regulation von Pink1, einer Parkinson-assoziierten Kinase, die in gesunden Zellen als mitochondrialer Stresssensor agiert. Als Folge auf eine starke ...
Structural and Functional Characterization of Human Transcription-regulating Kinases
(2024-03-12)
(noch nicht zugänglich / not yet accessible)
Biochemical and structural studies of NOD-like receptors and their inhibition by small molecule inhibitors
(2023-03-07)
NOD-like receptors (NLRs) are innate immune sensors that can form inflammasomes driving pyroptosis. NLRP3 is the best studied member of the NLRs to date, and its dysregulation has been linked to human diseases relevant to ...