Fakultäten der Universität Bonn: Suche
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Optimal Numerical Basis Functions in the Partition of Unity Method
(2024-04-08)
Partial differential equations (PDE) arise from the modeling of a wide range of physical problems and knowing how to solve them is of large interest in many industrial undertakings. One numerical method to solve PDE is the ...
The role of the NLRP3 inflammasome in microglial senescence in tauopathies
(2024-03-12)
Background: Tauopathies including Alzheimer’s Disease and Frontotemporal Dementia are neurodegenerative disorders characterized by abnormal tau accumulation. Senescent cells, which present with a potentially ...
Epidemiologic analyses of large-scale ophthalmic datasets
(2024-03-06)
In this thesis different epidemiological approaches were used to gather and evaluate various large datasets in order to address specific research questions in the field of ophthalmology. According to the individual research ...
Developmental programming of adipose tissue by maternal obesity
(2024-03-25)
Tissue-resident macrophages are an integral part of the innate immune system, but their biology is not well understood in the context of metabolic diseases. Distinctive Resident macrophage populations are identified in ...
Protein markers of inflammation and ageing in a European multi-centre dementia cohort
(2024-03-01)
Inflammation plays a key role in Alzheimerʼs disease (AD) progression. Microglia in the AD brain are exposed to pathological amyloid β (Aβ42) and tau peptide aggregates, resulting in the NLRP3 inflammasome activation ...
Organization principles of thalamocortical input onto deep-layer inhibitory neurons of the barrel cortex
(2024-02-28)
Thalamus functions as the main route by which incoming sensory information reaches the cerebral cortex. Thalamic nuclei will receive input from the sensory receptors in the periphery and relay it to different areas in the ...
Prävalenz der Aufmerksamkeitsdefizits-/Hyperaktivitätsstörung bei Menschen mit einer substanzbezogenen Störung: Eine Metaanalyse
(2024-03-12)
Substanzbezogene Störungen (SUD) haben erheblichen Einfluss auf unser Gesundheits-system. Die Hospitalisierung von Patient*innen mit einer SUD geht oft mit Komplikationen einher und hat in den letzten Jahren zugenommen. ...
Generative Adversarial Networks for Semantic Image Synthesis and Unconditional Synthesis with Limited Data
(2024-02-15)
Generative modeling of images is an important task aimed at synthesizing new images that are indistinguishable from real samples. The ability to generate diverse, realistic- looking images holds numerous applications, ...
Various Phenomenological Aspects of the R-parity Violating MSSM
(2024-02-05)
The Standard Model (SM) faces both theoretical and experimental challenges that indicate the existence of physics beyond its current framework. Among the proposed extensions, supersymmetry (SUSY) emerges as a promising ...
Social-aware Robot Navigation based on Deep Reinforcement Learning
(2024-04-24)
With the increase of applications involving autonomous mobile robots, there is a growing need for them to navigate safely and effectively in environments shared with humans. In recent years, social-aware robot navigation ...