Fakultäten der Universität Bonn: Suche
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Underwater flight in sea turtles and plesiosaurs: Dissection, muscle reconstructions, analog models, and finite element structure analyses inform on flipper twisting and muscle forces in plesiosaurs
(2020-08-13)
This dissertation contributes to our understanding of plesiosaur locomotion by providing foreflipper and hindflipper muscle reconstructions and studying aspects of their muscle physiology (functions, forces, muscle length ......
The Role of TRIM71 in Male Germ Cell Development
(2020-09-02)
Germ cells are the key to continuation of life as they are the unique cell lineage capable to transfer the complete genetic information to the next generation. Both, infertility and testicular cancers are usually originating ......
Simultaneous identification of nucleotide-modified aptamers with different properties by multiplexed click-SELEX
(2020-06-18)
Voltage-gated sodium channels (VGSC) are important key regulators in excitable tissue that initiate and propagate the action potential in specifically excitable tissue such as brain nerves or muscle. In order to understand ...
Design & generation of an efficient E. coli cell-factory for the overproduction of the compatible solutes ectoine & hydroxyectoine
(2020-07-01)
The compatible solutes ectoine and hydroxyectoine are produced by halophilic or halotolerant bacteria in order to balance and adapt to osmotic alterations in their habitat. Besides this, the potent ability of these compounds ...
Studien zur oxidativen Faltung des Faktor-XIIIa-Inhibitors Tridegin
(2020-11-16)
Diese Dissertation beschäftigt sich mit der umfassenden Charakterisierung des Naturstoffs Tridegin. Dieses cysteinreiche, 66 Aminosäuren lange Peptid ist ein spezifischer Inhibitor des letzten Schrittes der Blutgerinnungskaskade, ......
Studies on the oxidative folding of factor XIIIa inhibitor tridegin
This PhD thesis deals with the detailed characterization of the natural compound tridegin. This cysteine-rich 66mer peptide ......
Studies on the oxidative folding of factor XIIIa inhibitor tridegin
This PhD thesis deals with the detailed characterization of the natural compound tridegin. This cysteine-rich 66mer peptide ......
Eosinophil Extracellular DNA Trap Cell Death (EETosis) occurs as a life-cycle stage-specific response to filariae
(2020-06-25)
Filarial nematodes represent a great burden of human morbidity causing diseases like onchocerciasis and lymphatic filariasis. The lack of a vaccination and a short-term therapy with a macrofilaricidal effect hampers the ......
SRPK2 regulates active zone ultrastructure and RIM1 phosphorylation to tune presynaptic function and plasticity
(2020-07-30)
Chemical synapses communicate through the release of neurotransmitter-filled synaptic vesicles into the synaptic cleft. Synapses are able to dynamically adapt to the changes in the neuronal network by strengthening or ...
Aktivierung des angeborenen Immunsystems im Zentralnervensystem nach subchronischer Alkoholbehandlung im Mausmodell
(2020-06-03)
Alkohol ist als kulturell anerkanntes Rauschmittel in seinen ökonomischen, sozialen und gesundheitlichen Risiken weiterhin unterschätzt. In der Literatur zeigen sich Hinweise auf die Relevanz unterschiedlicher Trinkmuster ...
The role of the endocannabinoid system in stress-related disorders and neuroimmune communication
(2020-05-04)
In the last decades, increasing evidence suggests that inflammatory processes play an important role in the development of psychiatric disorders, such as anxiety and depression. Psychosocial stress – one of the main ...
Investigating the neural circuitry of the Mushroom body calyx in Drosophila melanogaster
(2020-07-15)
In Drosophila melanogaster, the mushroom body (MB) is essential for the formation and retrieval of olfactory associative memories. Within its input region, the MB calyx, olfactory information is delivered from second order ...