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The role of diacylglycerol acyltransferase 1 in hepatic medium-chain fatty acid metabolism
(2020-01-28)
Fatty acids form a class of important biomolecules, serving as essential elements of lipid molecules. Stored in triacylglycerol (TAG), the main constituent of plant oils and animal fats, they from an inseparable part of ......
Creld1 controls T cell homeostasis in mouse and human
(2020-07-07)
Cysteine-rich with EGF-like domains 1 (Creld1) was recently found to be fundamental for the VEGF-mediated activation of NFATc1 during heart development. Creld1 complete KO in mice is lethal due to developmental problems ...
Regulation of branched-chain amino acid metabolism in major metabolic tissues of dairy cows during late pregnancy and early lactation
(2020-04-01)
For dairy cows, the transition from late pregnancy to early lactation is characterized by dramatic changes in endocrine status, nutrient utilization as well as tissue metabolism. Specific metabolic processes, e.g., in ......
Der Übergang von der späten Trächtigkeit zur frühen Laktation ist bei Milchkühen mit drastischen Veränderungen des endokrinen Status, der Nährstoffverwertung sowie des Gewebestoffwechsels verbunden. Spezielle Stoffwechselprozesse, ......
Der Übergang von der späten Trächtigkeit zur frühen Laktation ist bei Milchkühen mit drastischen Veränderungen des endokrinen Status, der Nährstoffverwertung sowie des Gewebestoffwechsels verbunden. Spezielle Stoffwechselprozesse, ......
Function and diversity of myeloid cells during chronic inflammation in non-lymphoid organs
(2020-03-10)
Different immune cells play a major role in maintaining tissue homeostasis, tissue repair but also in inflammation. Tissue integrity is mainly controlled by tissue regulatory T cells (Tregs), type 2 innate ...
Essential and complementary function of dendritic cell subsets during immunotherapy
(2020-03-11)
T lymphocytes are critical components of the adaptive immune system that protects us against a variety of infections. However, during chronic infections such as with HIV, HCV and HBV as well as cancers, T cells become ...
Studien zur Total- und Biosynthese von PR Toxin
(2020-03-06)
Diese Arbeit beschäftigt sich mit dem Pilzgift PR Toxin, welches aus Penicillium roqueforti isoliert werden kann. Es wurden einerseits drei Ansätze für eine Totalsynthese entwickelt und andererseits grundlegende Arbeiten ...
Population size estimates based on the frequency of genetically assigned parent–offspring pairs within a subsample
(2020-07-24)
Estimating population density as precise as possible is a key premise for managing wild animal species. This can be a challenging task if the species in question is elusive or, due to high quantities, hard to count. We ...
Intrasexual selection: Kin competition increases male-male territorial aggression in a monogamous cichlid fish
(2020-09-12)
During intrasexual competition, individuals of the same sex compete for access to breeding sites and mating partners, often accompanied by aggressive behavior. Kin selection theory predicts different kin-directed social ...
Functional and cellular heterogeneity of the myeloid cell system
(2020-11-09)
Cells of the myeloid lineage form the innate part of the immune system and are characterized by a high level of functional plasticity, which is required to address the diverse set of functions of these mononuclear cells. ...
Fluorescent proteins for two-photon FLIM analysis of presynaptic protein interactions
(2020-06-10)
Monitoring Förster Resonance Energy Transfer (FRET) between fluorescent proteins (FPs) fused to proteins of interest is a powerful approach to study dynamic interactions of cellular proteins in living cells. The choice of ...